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Article: Tyrosinase inhibition constituents from the roots of Morus australis

TitleTyrosinase inhibition constituents from the roots of Morus australis
Authors
KeywordsMorus australis
Phenolic compounds
Roots
Tyrosinase inhibition
Issue Date2012
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/fitote
Citation
Fitoterapia, 2012, v. 83 n. 6, p. 1008-1013 How to Cite?
Abstract
The phytochemical profiles of Morus australis roots, stems and twigs were firstly compared by HPLC analysis. It was found that Morus australis stem extract mainly contained one known tyrosinase inhibitor, oxyresveratrol, while its root and twig extract might contain some unknown potential tyrosinase inhibitors. The root extract of Morus australis was further investigated in this study. One new compound, austraone A, together with 21 known compounds, was isolated and their structures were identified by interpretation of MS and NMR data. In the tyrosinase inhibitory testing, some of them, such as oxyresveratrol, moracenin D, sanggenon T, and kuwanon O, exhibited stronger tyrosinase inhibitory activities than that of kojic acid. These results suggested the Morus australis root extract as a good source of natural tyrosinase inhibitors with a great potential to be used in foods as anti-browning agents and in cosmetics as skin-whitening agents. © 2012 Elsevier B.V. All rights reserved.
Persistent Identifierhttp://hdl.handle.net/10722/165936
ISSN
2013 Impact Factor: 2.216
2013 SCImago Journal Rankings: 0.879
ISI Accession Number ID
References

 

Author Affiliations
  1. The University of Hong Kong
  2. Jiangnan University
DC FieldValueLanguage
dc.contributor.authorZheng, ZPen_HK
dc.contributor.authorTan, HYen_HK
dc.contributor.authorWang, Men_HK
dc.date.accessioned2012-09-20T08:25:38Z-
dc.date.available2012-09-20T08:25:38Z-
dc.date.issued2012en_HK
dc.identifier.citationFitoterapia, 2012, v. 83 n. 6, p. 1008-1013en_HK
dc.identifier.issn0367-326Xen_HK
dc.identifier.urihttp://hdl.handle.net/10722/165936-
dc.description.abstractThe phytochemical profiles of Morus australis roots, stems and twigs were firstly compared by HPLC analysis. It was found that Morus australis stem extract mainly contained one known tyrosinase inhibitor, oxyresveratrol, while its root and twig extract might contain some unknown potential tyrosinase inhibitors. The root extract of Morus australis was further investigated in this study. One new compound, austraone A, together with 21 known compounds, was isolated and their structures were identified by interpretation of MS and NMR data. In the tyrosinase inhibitory testing, some of them, such as oxyresveratrol, moracenin D, sanggenon T, and kuwanon O, exhibited stronger tyrosinase inhibitory activities than that of kojic acid. These results suggested the Morus australis root extract as a good source of natural tyrosinase inhibitors with a great potential to be used in foods as anti-browning agents and in cosmetics as skin-whitening agents. © 2012 Elsevier B.V. All rights reserved.en_HK
dc.languageengen_US
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/fitoteen_HK
dc.relation.ispartofFitoterapiaen_HK
dc.subjectMorus australisen_HK
dc.subjectPhenolic compoundsen_HK
dc.subjectRootsen_HK
dc.subjectTyrosinase inhibitionen_HK
dc.titleTyrosinase inhibition constituents from the roots of Morus australisen_HK
dc.typeArticleen_HK
dc.identifier.emailWang, M: mfwang@hku.hken_HK
dc.identifier.authorityWang, M=rp00800en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1016/j.fitote.2012.06.001en_HK
dc.identifier.pmid22698714-
dc.identifier.scopuseid_2-s2.0-84863984322en_HK
dc.identifier.hkuros206146en_US
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-84863984322&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume83en_HK
dc.identifier.issue6en_HK
dc.identifier.spage1008en_HK
dc.identifier.epage1013en_HK
dc.identifier.isiWOS:000308116600005-
dc.publisher.placeNetherlandsen_HK
dc.identifier.scopusauthoridZheng, ZP=8451746600en_HK
dc.identifier.scopusauthoridTan, HY=54391749200en_HK
dc.identifier.scopusauthoridWang, M=7406691844en_HK
dc.identifier.citeulike10780493-

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