Article: Tyrosinase inhibition constituents from the roots of Morus australis

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TitleTyrosinase inhibition constituents from the roots of Morus australis
AuthorsZheng, ZP1
Tan, HY1
Wang, M1
KeywordsMorus australis
Phenolic compounds
Roots
Tyrosinase inhibition
Issue Date2012
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/fitote
CitationFitoterapia, 2012, v. 83 n. 6, p. 1008-1013 [How to Cite?]
DOI: http://dx.doi.org/10.1016/j.fitote.2012.06.001
AbstractThe phytochemical profiles of Morus australis roots, stems and twigs were firstly compared by HPLC analysis. It was found that Morus australis stem extract mainly contained one known tyrosinase inhibitor, oxyresveratrol, while its root and twig extract might contain some unknown potential tyrosinase inhibitors. The root extract of Morus australis was further investigated in this study. One new compound, austraone A, together with 21 known compounds, was isolated and their structures were identified by interpretation of MS and NMR data. In the tyrosinase inhibitory testing, some of them, such as oxyresveratrol, moracenin D, sanggenon T, and kuwanon O, exhibited stronger tyrosinase inhibitory activities than that of kojic acid. These results suggested the Morus australis root extract as a good source of natural tyrosinase inhibitors with a great potential to be used in foods as anti-browning agents and in cosmetics as skin-whitening agents. © 2012 Elsevier B.V. All rights reserved.
ISSN0367-326X
2011 Impact Factor: 1.848
2011 SCImago Journal Rankings: 0.086
DOIhttp://dx.doi.org/10.1016/j.fitote.2012.06.001
ReferencesReferences in Scopus
DC Field
Value
dc.contributor.authorZheng, ZP
dc.contributor.authorTan, HY
dc.contributor.authorWang, M
dc.date.accessioned2012-09-20T08:25:38Z
dc.date.available2012-09-20T08:25:38Z
dc.date.issued2012
dc.description.abstractThe phytochemical profiles of Morus australis roots, stems and twigs were firstly compared by HPLC analysis. It was found that Morus australis stem extract mainly contained one known tyrosinase inhibitor, oxyresveratrol, while its root and twig extract might contain some unknown potential tyrosinase inhibitors. The root extract of Morus australis was further investigated in this study. One new compound, austraone A, together with 21 known compounds, was isolated and their structures were identified by interpretation of MS and NMR data. In the tyrosinase inhibitory testing, some of them, such as oxyresveratrol, moracenin D, sanggenon T, and kuwanon O, exhibited stronger tyrosinase inhibitory activities than that of kojic acid. These results suggested the Morus australis root extract as a good source of natural tyrosinase inhibitors with a great potential to be used in foods as anti-browning agents and in cosmetics as skin-whitening agents. © 2012 Elsevier B.V. All rights reserved.
dc.description.natureLink_to_subscribed_fulltext
dc.identifier.citationFitoterapia, 2012, v. 83 n. 6, p. 1008-1013 [How to Cite?]
DOI: http://dx.doi.org/10.1016/j.fitote.2012.06.001
dc.identifier.citeulike10780493
dc.identifier.doihttp://dx.doi.org/10.1016/j.fitote.2012.06.001
dc.identifier.epage1013
dc.identifier.hkuros206146
dc.identifier.issn0367-326X
2011 Impact Factor: 1.848
2011 SCImago Journal Rankings: 0.086
dc.identifier.issue6
dc.identifier.scopuseid_2-s2.0-84863984322
dc.identifier.spage1008
dc.identifier.urihttp://hdl.handle.net/10722/165936
dc.identifier.volume83
dc.languageeng
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/fitote
dc.publisher.placeNetherlands
dc.relation.ispartofFitoterapia
dc.relation.referencesReferences in Scopus
dc.subjectMorus australis
dc.subjectPhenolic compounds
dc.subjectRoots
dc.subjectTyrosinase inhibition
dc.titleTyrosinase inhibition constituents from the roots of Morus australis
dc.typeArticle
Author Affiliations
  1. The University of Hong Kong