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Article: Tyrosinase inhibition constituents from the roots of Morus australis
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TitleTyrosinase inhibition constituents from the roots of Morus australis
 
AuthorsZheng, ZP2 1
Tan, HY1
Wang, M1
 
KeywordsMorus australis
Phenolic compounds
Roots
Tyrosinase inhibition
 
Issue Date2012
 
PublisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/fitote
 
CitationFitoterapia, 2012, v. 83 n. 6, p. 1008-1013 [How to Cite?]
DOI: http://dx.doi.org/10.1016/j.fitote.2012.06.001
 
AbstractThe phytochemical profiles of Morus australis roots, stems and twigs were firstly compared by HPLC analysis. It was found that Morus australis stem extract mainly contained one known tyrosinase inhibitor, oxyresveratrol, while its root and twig extract might contain some unknown potential tyrosinase inhibitors. The root extract of Morus australis was further investigated in this study. One new compound, austraone A, together with 21 known compounds, was isolated and their structures were identified by interpretation of MS and NMR data. In the tyrosinase inhibitory testing, some of them, such as oxyresveratrol, moracenin D, sanggenon T, and kuwanon O, exhibited stronger tyrosinase inhibitory activities than that of kojic acid. These results suggested the Morus australis root extract as a good source of natural tyrosinase inhibitors with a great potential to be used in foods as anti-browning agents and in cosmetics as skin-whitening agents. © 2012 Elsevier B.V. All rights reserved.
 
ISSN0367-326X
2013 Impact Factor: 2.216
2013 SCImago Journal Rankings: 0.879
 
DOIhttp://dx.doi.org/10.1016/j.fitote.2012.06.001
 
ReferencesReferences in Scopus
 
DC FieldValue
dc.contributor.authorZheng, ZP
 
dc.contributor.authorTan, HY
 
dc.contributor.authorWang, M
 
dc.date.accessioned2012-09-20T08:25:38Z
 
dc.date.available2012-09-20T08:25:38Z
 
dc.date.issued2012
 
dc.description.abstractThe phytochemical profiles of Morus australis roots, stems and twigs were firstly compared by HPLC analysis. It was found that Morus australis stem extract mainly contained one known tyrosinase inhibitor, oxyresveratrol, while its root and twig extract might contain some unknown potential tyrosinase inhibitors. The root extract of Morus australis was further investigated in this study. One new compound, austraone A, together with 21 known compounds, was isolated and their structures were identified by interpretation of MS and NMR data. In the tyrosinase inhibitory testing, some of them, such as oxyresveratrol, moracenin D, sanggenon T, and kuwanon O, exhibited stronger tyrosinase inhibitory activities than that of kojic acid. These results suggested the Morus australis root extract as a good source of natural tyrosinase inhibitors with a great potential to be used in foods as anti-browning agents and in cosmetics as skin-whitening agents. © 2012 Elsevier B.V. All rights reserved.
 
dc.description.naturelink_to_subscribed_fulltext
 
dc.identifier.citationFitoterapia, 2012, v. 83 n. 6, p. 1008-1013 [How to Cite?]
DOI: http://dx.doi.org/10.1016/j.fitote.2012.06.001
 
dc.identifier.citeulike10780493
 
dc.identifier.doihttp://dx.doi.org/10.1016/j.fitote.2012.06.001
 
dc.identifier.epage1013
 
dc.identifier.hkuros206146
 
dc.identifier.issn0367-326X
2013 Impact Factor: 2.216
2013 SCImago Journal Rankings: 0.879
 
dc.identifier.issue6
 
dc.identifier.pmid22698714
 
dc.identifier.scopuseid_2-s2.0-84863984322
 
dc.identifier.spage1008
 
dc.identifier.urihttp://hdl.handle.net/10722/165936
 
dc.identifier.volume83
 
dc.languageeng
 
dc.publisherElsevier BV. The Journal's web site is located at http://www.elsevier.com/locate/fitote
 
dc.publisher.placeNetherlands
 
dc.relation.ispartofFitoterapia
 
dc.relation.referencesReferences in Scopus
 
dc.subjectMorus australis
 
dc.subjectPhenolic compounds
 
dc.subjectRoots
 
dc.subjectTyrosinase inhibition
 
dc.titleTyrosinase inhibition constituents from the roots of Morus australis
 
dc.typeArticle
 
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Author Affiliations
  1. The University of Hong Kong
  2. Jiangnan University