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Conference Paper: Genomics approach to identify drug transporter ABCF1 associated with liver cancer recurrence and chemo-resistance

TitleGenomics approach to identify drug transporter ABCF1 associated with liver cancer recurrence and chemo-resistance
Authors
Issue Date2012
PublisherAmerican Association for Cancer Research.
Citation
The Annual Meeting of the American Association for Cancer Research (AACR 2012), Chicago, IL., 31 March-4 April 2012. How to Cite?
AbstractBACKGROUND: Liver cancer is the third leading cause of cancer death globally. Surgery is the mainstay for early stage patients with the best survival outcome, but cancer recurrence is still common after curative surgery. Chemotherapy has been widely used to treat advanced liver cancer but with marginal efficacy. There is an urgent need to elucidate the key genes that regulate recurrence and chemo-resistance in the clinical situation. Recently, we have demonstrated that the novel growth factor granulin-epithelin precursor (GEP) is associated with chemo-resistance and recurrence-free survival. GEP has been identified as a potential therapeutic target for liver cancer in our ...
DescriptionPoster Session 33 - New Models, Screens, and Diagnostics for Target Identification: abstract no. 882
Persistent Identifierhttp://hdl.handle.net/10722/165657

 

DC FieldValueLanguage
dc.contributor.authorCheung, STen_US
dc.contributor.authorCheung, PFYen_US
dc.contributor.authorCheng, CKCen_US
dc.contributor.authorFan, STen_US
dc.date.accessioned2012-09-20T08:21:42Z-
dc.date.available2012-09-20T08:21:42Z-
dc.date.issued2012en_US
dc.identifier.citationThe Annual Meeting of the American Association for Cancer Research (AACR 2012), Chicago, IL., 31 March-4 April 2012.en_US
dc.identifier.urihttp://hdl.handle.net/10722/165657-
dc.descriptionPoster Session 33 - New Models, Screens, and Diagnostics for Target Identification: abstract no. 882-
dc.description.abstractBACKGROUND: Liver cancer is the third leading cause of cancer death globally. Surgery is the mainstay for early stage patients with the best survival outcome, but cancer recurrence is still common after curative surgery. Chemotherapy has been widely used to treat advanced liver cancer but with marginal efficacy. There is an urgent need to elucidate the key genes that regulate recurrence and chemo-resistance in the clinical situation. Recently, we have demonstrated that the novel growth factor granulin-epithelin precursor (GEP) is associated with chemo-resistance and recurrence-free survival. GEP has been identified as a potential therapeutic target for liver cancer in our ...-
dc.languageengen_US
dc.publisherAmerican Association for Cancer Research.-
dc.relation.ispartofAnnual Meeting of the American Association for Cancer Research, AACR 2012en_US
dc.titleGenomics approach to identify drug transporter ABCF1 associated with liver cancer recurrence and chemo-resistanceen_US
dc.typeConference_Paperen_US
dc.identifier.emailCheung, ST: stcheung@hkucc.hku.hken_US
dc.identifier.emailCheung, PFY: cphyllis@hkucc.hku.hken_US
dc.identifier.emailCheng, CKC: ckccheng@hkucc.hku.hken_US
dc.identifier.emailFan, ST: stfan@hku.hken_US
dc.identifier.authorityCheung, ST=rp00457en_US
dc.identifier.authorityFan, ST=rp00355en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.hkuros211418en_US
dc.publisher.placeUnited States-
dc.description.otherThe Annual Meeting of the American Association for Cancer Research (AACR 2012), Chicago, IL., 31 March-4 April 2012.-

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