Water uptake and diffusion in PHBV tissue engineering scaffolds and non-porous thin films

Abstract

Radiation induced chemical changes in polyhydroxymethylacrylate gels (PHEMAG) used in 3D radiation dosimetry have been studied using Raman spectroscopy. The gels were irradiated to low energy xray and the polymerization of PHEMAG gels are followed by the change of Raman shift intensity of the carbon covalent bond of PHEMAG originated from both monomer and the cross-linker. The variation in peak intensities with absorbed dose was observed. The peak intensities of covalent bond of carbon in the polymer gels decrease with increasing tube voltage. This indicates that polymerization increase with higher dose of radiation. The concentration of monomers was also varied. Results show that the sensitivity of polymer gel dosimeter increases as the monomer concentration increases.