File Download
 
 
Supplementary

Conference Paper: Increasing diffusion time improves in vivo DWI sensitivity to liver fibrosis
  • Basic View
  • Metadata View
  • XML View
TitleIncreasing diffusion time improves in vivo DWI sensitivity to liver fibrosis
 
AuthorsGao, DS
Yang, J
Cheung, MMH
Chow, AMK
Fan, S
Man, K
Wu, EX
 
Issue Date2012
 
PublisherInternational Society of Magnetic Resonance in Medicine.
 
CitationThe 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of the 20th ISMRM, 2012, no. 0404 [How to Cite?]
 
AbstractIn liver fibrosis, the structural damage on cellular scale may modify the restricted diffusion behavior of water molecules in the intra- and extracellular space. In this study, we examined whether different diffusion times would yield different sensitivities in detecting the pathological alterations in tissue microstructure during liver fibrogenesis in an experimental rat model. Our results demonstrated that true diffusion coefficient (DTrue) measured with long diffusion time was highly sensitive in detecting and accessing subtle changes in tissue microstructure during liver fibrogenesis.
 
DescriptionTheme: Adapting MR in a Changing World
Oral Presentation - Session 40: Hepatobiliary & Gastrointestinal: no. 0404
 
DC FieldValue
dc.contributor.authorGao, DS
 
dc.contributor.authorYang, J
 
dc.contributor.authorCheung, MMH
 
dc.contributor.authorChow, AMK
 
dc.contributor.authorFan, S
 
dc.contributor.authorMan, K
 
dc.contributor.authorWu, EX
 
dc.date.accessioned2012-09-20T08:16:05Z
 
dc.date.available2012-09-20T08:16:05Z
 
dc.date.issued2012
 
dc.description.abstractIn liver fibrosis, the structural damage on cellular scale may modify the restricted diffusion behavior of water molecules in the intra- and extracellular space. In this study, we examined whether different diffusion times would yield different sensitivities in detecting the pathological alterations in tissue microstructure during liver fibrogenesis in an experimental rat model. Our results demonstrated that true diffusion coefficient (DTrue) measured with long diffusion time was highly sensitive in detecting and accessing subtle changes in tissue microstructure during liver fibrogenesis.
 
dc.description.naturelink_to_OA_fulltext
 
dc.descriptionTheme: Adapting MR in a Changing World
 
dc.descriptionOral Presentation - Session 40: Hepatobiliary & Gastrointestinal: no. 0404
 
dc.description.otherThe 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of the 20th ISMRM, 2012, no. 0404
 
dc.identifier.citationThe 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of the 20th ISMRM, 2012, no. 0404 [How to Cite?]
 
dc.identifier.hkuros207283
 
dc.identifier.urihttp://hdl.handle.net/10722/165181
 
dc.languageeng
 
dc.publisherInternational Society of Magnetic Resonance in Medicine.
 
dc.publisher.placeAustralia
 
dc.relation.ispartofProceedings of the 20th Annual Meeting of the International Society of Magnetic Resonance in Medicine, ISMRM 2012
 
dc.titleIncreasing diffusion time improves in vivo DWI sensitivity to liver fibrosis
 
dc.typeConference_Paper
 
<?xml encoding="utf-8" version="1.0"?>
<item><contributor.author>Gao, DS</contributor.author>
<contributor.author>Yang, J</contributor.author>
<contributor.author>Cheung, MMH</contributor.author>
<contributor.author>Chow, AMK</contributor.author>
<contributor.author>Fan, S</contributor.author>
<contributor.author>Man, K</contributor.author>
<contributor.author>Wu, EX</contributor.author>
<date.accessioned>2012-09-20T08:16:05Z</date.accessioned>
<date.available>2012-09-20T08:16:05Z</date.available>
<date.issued>2012</date.issued>
<identifier.citation>The 20th Annual Meeting &amp; Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of the 20th ISMRM, 2012, no. 0404</identifier.citation>
<identifier.uri>http://hdl.handle.net/10722/165181</identifier.uri>
<description>Theme: Adapting MR in a Changing World</description>
<description>Oral Presentation - Session 40: Hepatobiliary &amp; Gastrointestinal: no. 0404</description>
<description.abstract>In liver fibrosis, the structural damage on cellular scale may modify the restricted diffusion behavior of water molecules in the intra- and extracellular space. In this study, we examined whether different diffusion times would yield different sensitivities in detecting the pathological alterations in tissue microstructure during liver fibrogenesis in an experimental rat model. Our results demonstrated that true diffusion coefficient (DTrue) measured with long diffusion time was highly sensitive in detecting and accessing subtle changes in tissue microstructure during liver fibrogenesis.</description.abstract>
<language>eng</language>
<publisher>International Society of Magnetic Resonance in Medicine.</publisher>
<relation.ispartof>Proceedings of the 20th Annual Meeting of the International Society of Magnetic Resonance in Medicine, ISMRM 2012</relation.ispartof>
<title>Increasing diffusion time improves in vivo DWI sensitivity to liver fibrosis</title>
<type>Conference_Paper</type>
<description.nature>link_to_OA_fulltext</description.nature>
<identifier.hkuros>207283</identifier.hkuros>
<publisher.place>Australia</publisher.place>
<description.other>The 20th Annual Meeting &amp; Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of the 20th ISMRM, 2012, no. 0404</description.other>
<bitstream.url>http://hub.hku.hk/bitstream/10722/165181/1/re01.htm</bitstream.url>
</item>