Conference Paper: Increasing diffusion time improves in vivo DWI sensitivity to liver fibrosis
| Title | Increasing diffusion time improves in vivo DWI sensitivity to liver fibrosis |
|---|---|
| Authors | Gao, DS Yang, J Cheung, MMH Chow, AMK Fan, S Man, K Wu, EX |
| Issue Date | 2012 |
| Publisher | International Society of Magnetic Resonance in Medicine. |
| Citation | The 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of the 20th ISMRM, 2012, no. 0404 [How to Cite?] |
| Abstract | In liver fibrosis, the structural damage on cellular scale may modify the restricted diffusion behavior of water molecules in the intra- and extracellular space. In this study, we examined whether different diffusion times would yield different sensitivities in detecting the pathological alterations in tissue microstructure during liver fibrogenesis in an experimental rat model. Our results demonstrated that true diffusion coefficient (DTrue) measured with long diffusion time was highly sensitive in detecting and accessing subtle changes in tissue microstructure during liver fibrogenesis. |
| Description | Theme: Adapting MR in a Changing World Oral Presentation - Session 40: Hepatobiliary & Gastrointestinal: no. 0404 |
| dc.contributor.author | Gao, DS |
|---|---|
| dc.contributor.author | Yang, J |
| dc.contributor.author | Cheung, MMH |
| dc.contributor.author | Chow, AMK |
| dc.contributor.author | Fan, S |
| dc.contributor.author | Man, K |
| dc.contributor.author | Wu, EX |
| dc.date.accessioned | 2012-09-20T08:16:05Z |
| dc.date.available | 2012-09-20T08:16:05Z |
| dc.date.issued | 2012 |
| dc.description.abstract | In liver fibrosis, the structural damage on cellular scale may modify the restricted diffusion behavior of water molecules in the intra- and extracellular space. In this study, we examined whether different diffusion times would yield different sensitivities in detecting the pathological alterations in tissue microstructure during liver fibrogenesis in an experimental rat model. Our results demonstrated that true diffusion coefficient (DTrue) measured with long diffusion time was highly sensitive in detecting and accessing subtle changes in tissue microstructure during liver fibrogenesis. |
| dc.description.nature | link_to_OA_fulltext |
| dc.description | Theme: Adapting MR in a Changing World |
| dc.description | Oral Presentation - Session 40: Hepatobiliary & Gastrointestinal: no. 0404 |
| dc.description.other | The 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of the 20th ISMRM, 2012, no. 0404 |
| dc.identifier.citation | The 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of the 20th ISMRM, 2012, no. 0404 [How to Cite?] |
| dc.identifier.hkuros | 207283 |
| dc.identifier.uri | http://hdl.handle.net/10722/165181 |
| dc.language | eng |
| dc.publisher | International Society of Magnetic Resonance in Medicine. |
| dc.publisher.place | Australia |
| dc.relation.ispartof | Proceedings of the 20th Annual Meeting of the International Society of Magnetic Resonance in Medicine, ISMRM 2012 |
| dc.title | Increasing diffusion time improves in vivo DWI sensitivity to liver fibrosis |
| dc.type | Conference_Paper |