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Conference Paper: Increasing diffusion time improves in vivo DWI sensitivity to liver fibrosis

TitleIncreasing diffusion time improves in vivo DWI sensitivity to liver fibrosis
Authors
Issue Date2012
PublisherInternational Society of Magnetic Resonance in Medicine.
Citation
The 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of the 20th ISMRM, 2012, no. 0404 How to Cite?
Abstract
In liver fibrosis, the structural damage on cellular scale may modify the restricted diffusion behavior of water molecules in the intra- and extracellular space. In this study, we examined whether different diffusion times would yield different sensitivities in detecting the pathological alterations in tissue microstructure during liver fibrogenesis in an experimental rat model. Our results demonstrated that true diffusion coefficient (DTrue) measured with long diffusion time was highly sensitive in detecting and accessing subtle changes in tissue microstructure during liver fibrogenesis.
DescriptionTheme: Adapting MR in a Changing World
Persistent Identifierhttp://hdl.handle.net/10722/165181

 

DC FieldValueLanguage
dc.contributor.authorGao, DSen_US
dc.contributor.authorYang, Jen_US
dc.contributor.authorCheung, MMHen_US
dc.contributor.authorChow, AMKen_US
dc.contributor.authorFan, Sen_US
dc.contributor.authorMan, Ken_US
dc.contributor.authorWu, EXen_US
dc.date.accessioned2012-09-20T08:16:05Z-
dc.date.available2012-09-20T08:16:05Z-
dc.date.issued2012en_US
dc.identifier.citationThe 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of the 20th ISMRM, 2012, no. 0404en_US
dc.identifier.urihttp://hdl.handle.net/10722/165181-
dc.descriptionTheme: Adapting MR in a Changing World-
dc.descriptionOral Presentation - Session 40: Hepatobiliary & Gastrointestinal: no. 0404-
dc.description.abstractIn liver fibrosis, the structural damage on cellular scale may modify the restricted diffusion behavior of water molecules in the intra- and extracellular space. In this study, we examined whether different diffusion times would yield different sensitivities in detecting the pathological alterations in tissue microstructure during liver fibrogenesis in an experimental rat model. Our results demonstrated that true diffusion coefficient (DTrue) measured with long diffusion time was highly sensitive in detecting and accessing subtle changes in tissue microstructure during liver fibrogenesis.-
dc.languageengen_US
dc.publisherInternational Society of Magnetic Resonance in Medicine.-
dc.relation.ispartofProceedings of the 20th Annual Meeting of the International Society of Magnetic Resonance in Medicine, ISMRM 2012en_US
dc.titleIncreasing diffusion time improves in vivo DWI sensitivity to liver fibrosisen_US
dc.typeConference_Paperen_US
dc.identifier.emailGao, DS: issgao@hku.hken_US
dc.identifier.emailYang, J: yj1118@hkucc.hku.hk-
dc.identifier.emailCheung, MMH: thew@hku.hk-
dc.identifier.emailChow, AMK: amkchow@hkucc.hku.hk-
dc.identifier.emailFan, S: fanshj08@hkucc.hku.hk-
dc.identifier.emailMan, K: kwanman@hku.hk-
dc.identifier.emailWu, EX: ewu@eee.hku.hk-
dc.identifier.authorityMan, K=rp00417en_US
dc.description.naturelink_to_OA_fulltext-
dc.identifier.hkuros207283en_US
dc.publisher.placeAustralia-
dc.description.otherThe 20th Annual Meeting & Exihibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2012), Melbourne, Australia, 5-11 May 2012. In Proceedings of the 20th ISMRM, 2012, no. 0404-

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