File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: Structural abnormalities of the central auditory pathway in infants with nonsyndromic cleft lip and/or palate

TitleStructural abnormalities of the central auditory pathway in infants with nonsyndromic cleft lip and/or palate
Authors
KeywordsCentral auditory nervous system
Cleft lip and palate
Hearing impairment
Magnetic resonance imaging
Issue Date2012
PublisherAllen Press Inc. The Journal's web site is located at http://cpcj.allenpress.com
Citation
Cleft Palate-Craniofacial Journal, 2012, v. 49 n. 2, p. 137-145 How to Cite?
AbstractObjective: To investigate possible structural abnormalities of the central auditory pathway in infants with nonsyndromic cleft lip and/or palate (NSCL/P). Participants: Twenty-seven Chinese infants with NSCL/P, aged from 6 to 24 months. Intervention: Morphological magnetic resonance imaging (MRI) measurements of the central auditory nervous system (CANS) in infants with NSCL/P were analyzed and compared with those of age- and sex-matched normal controls. Results: No significant group differences were found in general brain measurements, including volumes of the brain stem and right hemisphere. However, infants with NSCL/P had statistically significantly smaller volumes of the left thalamus and left auditory cortex and notably decreased thickness of the left auditory cortex. Conclusion: Cortical abnormalities were more marked compared with other MRI measurements. Structural CANS abnormalities in infants with NSCL/P may be located mainly in the left cerebral hemisphere. The development and maturation of the auditory cortex in infants with NSCL/P may be abnormal when compared with those of normal children.
Persistent Identifierhttp://hdl.handle.net/10722/164631
ISSN
2010 Impact Factor: 0.77
2015 SCImago Journal Rankings: 0.685
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorYang, FFen_HK
dc.contributor.authorMcPherson, Ben_HK
dc.contributor.authorShu, Hen_HK
dc.contributor.authorXie, Nen_HK
dc.contributor.authorXiang, Ken_HK
dc.date.accessioned2012-09-20T08:07:07Z-
dc.date.available2012-09-20T08:07:07Z-
dc.date.issued2012en_HK
dc.identifier.citationCleft Palate-Craniofacial Journal, 2012, v. 49 n. 2, p. 137-145en_HK
dc.identifier.issn1055-6656en_HK
dc.identifier.urihttp://hdl.handle.net/10722/164631-
dc.description.abstractObjective: To investigate possible structural abnormalities of the central auditory pathway in infants with nonsyndromic cleft lip and/or palate (NSCL/P). Participants: Twenty-seven Chinese infants with NSCL/P, aged from 6 to 24 months. Intervention: Morphological magnetic resonance imaging (MRI) measurements of the central auditory nervous system (CANS) in infants with NSCL/P were analyzed and compared with those of age- and sex-matched normal controls. Results: No significant group differences were found in general brain measurements, including volumes of the brain stem and right hemisphere. However, infants with NSCL/P had statistically significantly smaller volumes of the left thalamus and left auditory cortex and notably decreased thickness of the left auditory cortex. Conclusion: Cortical abnormalities were more marked compared with other MRI measurements. Structural CANS abnormalities in infants with NSCL/P may be located mainly in the left cerebral hemisphere. The development and maturation of the auditory cortex in infants with NSCL/P may be abnormal when compared with those of normal children.en_HK
dc.languageengen_US
dc.publisherAllen Press Inc. The Journal's web site is located at http://cpcj.allenpress.comen_HK
dc.relation.ispartofCleft Palate-Craniofacial Journalen_HK
dc.subjectCentral auditory nervous systemen_HK
dc.subjectCleft lip and palateen_HK
dc.subjectHearing impairmenten_HK
dc.subjectMagnetic resonance imagingen_HK
dc.titleStructural abnormalities of the central auditory pathway in infants with nonsyndromic cleft lip and/or palateen_HK
dc.typeArticleen_HK
dc.identifier.emailMcPherson, B: dbmcpher@hkucc.hku.hken_HK
dc.identifier.authorityMcPherson, B=rp00937en_HK
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.1597/11-014en_HK
dc.identifier.pmid21848367-
dc.identifier.scopuseid_2-s2.0-84858591599en_HK
dc.identifier.hkuros207928en_US
dc.identifier.hkuros201909-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-84858591599&selection=ref&src=s&origin=recordpageen_HK
dc.identifier.volume49en_HK
dc.identifier.issue2en_HK
dc.identifier.spage137en_HK
dc.identifier.epage145en_HK
dc.identifier.eissn1545-1569-
dc.identifier.isiWOS:000314505300002-
dc.publisher.placeUnited Statesen_HK
dc.identifier.scopusauthoridYang, FF=54384481800en_HK
dc.identifier.scopusauthoridMcPherson, B=7006800770en_HK
dc.identifier.scopusauthoridShu, H=55110724500en_HK
dc.identifier.scopusauthoridXie, N=55110602100en_HK
dc.identifier.scopusauthoridXiang, K=55111145600en_HK

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats