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Article: A novel SERS-active tag based on bimetallic flowerlike Au-Ag nanoparticles

TitleA novel SERS-active tag based on bimetallic flowerlike Au-Ag nanoparticles
Authors
KeywordsAu-ag bimetallic
Core shell structure
Flowerlike shape
Folic acids
Sers tag
Issue Date2011
PublisherBentham Science Publishers Ltd. The Journal's web site is located at http://www.bentham.org/cnano/index.htm
Citation
Current Nanoscience, 2011, v. 7 n. 6, p. 969-978 How to Cite?
AbstractBimetallic nanoparticles have received considerable attention due to their unique optical, magnetic and other properties. Their composition, architecture, shape and size can be adjusted relatively easily in order to change their properties, which provide great potential for their diverse applications. Bimetallic Au-Ag nanoparticles are very attractive because they exhibit remarkable optical properties due to their surface plasmon resonance (SPR) absorption. In this investigation, a simple synthesis process for novel, bimetallic flowerlike Au-Ag composite nanoparticles was developed. Biocompatible folic acid-conjugated chitosan with flexible molecular chains were used as the structure-directing agent in nanoparticle synthesis. The structure and properties of Au-Ag nanoparticles were studied using a variety of analytical techniques including high resolution transmission electron microscopy. These nanoparticles contained an Au core and an Ag shell and the shape and thickness of the Ag shell could be easily controlled by varying the synthesis condition. The formation and growth of flowerlike bimetallic Au-Ag composite nanoparticles was investigated and its mechanism proposed. On the basis of flowerlike Au-Ag nanoparticles which can produce surface enhanced Raman scattering (SERS), a novel SERS tag was formed, which consisted of an Au-Ag flowerlike nanoparticle, embedded Rhodamine B (RhB, a Raman reporter molecule), and a folic acid-conjugated chitosan outer layer. This new SERS tag (RhB@Au-Ag tag) exhibited greatly increased SERS intensity of RhB and hence showed great potential for tumor cell targeting and detection. © 2011 Bentham Science Publishers.
Persistent Identifierhttp://hdl.handle.net/10722/164206
ISSN
2015 Impact Factor: 0.934
2015 SCImago Journal Rankings: 0.283

 

DC FieldValueLanguage
dc.contributor.authorLi, SYen_US
dc.contributor.authorWang, Men_US
dc.date.accessioned2012-09-20T07:56:36Z-
dc.date.available2012-09-20T07:56:36Z-
dc.date.issued2011en_US
dc.identifier.citationCurrent Nanoscience, 2011, v. 7 n. 6, p. 969-978en_US
dc.identifier.issn1573-4137-
dc.identifier.urihttp://hdl.handle.net/10722/164206-
dc.description.abstractBimetallic nanoparticles have received considerable attention due to their unique optical, magnetic and other properties. Their composition, architecture, shape and size can be adjusted relatively easily in order to change their properties, which provide great potential for their diverse applications. Bimetallic Au-Ag nanoparticles are very attractive because they exhibit remarkable optical properties due to their surface plasmon resonance (SPR) absorption. In this investigation, a simple synthesis process for novel, bimetallic flowerlike Au-Ag composite nanoparticles was developed. Biocompatible folic acid-conjugated chitosan with flexible molecular chains were used as the structure-directing agent in nanoparticle synthesis. The structure and properties of Au-Ag nanoparticles were studied using a variety of analytical techniques including high resolution transmission electron microscopy. These nanoparticles contained an Au core and an Ag shell and the shape and thickness of the Ag shell could be easily controlled by varying the synthesis condition. The formation and growth of flowerlike bimetallic Au-Ag composite nanoparticles was investigated and its mechanism proposed. On the basis of flowerlike Au-Ag nanoparticles which can produce surface enhanced Raman scattering (SERS), a novel SERS tag was formed, which consisted of an Au-Ag flowerlike nanoparticle, embedded Rhodamine B (RhB, a Raman reporter molecule), and a folic acid-conjugated chitosan outer layer. This new SERS tag (RhB@Au-Ag tag) exhibited greatly increased SERS intensity of RhB and hence showed great potential for tumor cell targeting and detection. © 2011 Bentham Science Publishers.-
dc.languageengen_US
dc.publisherBentham Science Publishers Ltd. The Journal's web site is located at http://www.bentham.org/cnano/index.htmen_US
dc.relation.ispartofCurrent Nanoscienceen_US
dc.subjectAu-ag bimetallic-
dc.subjectCore shell structure-
dc.subjectFlowerlike shape-
dc.subjectFolic acids-
dc.subjectSers tag-
dc.titleA novel SERS-active tag based on bimetallic flowerlike Au-Ag nanoparticlesen_US
dc.typeArticleen_US
dc.identifier.emailWang, M: memwang@hku.hken_US
dc.identifier.authorityWang, M=rp00185en_US
dc.description.naturelink_to_subscribed_fulltext-
dc.identifier.doi10.2174/157341311798220583-
dc.identifier.scopuseid_2-s2.0-82155193000-
dc.identifier.hkuros207451en_US
dc.identifier.volume7en_US
dc.identifier.issue6-
dc.identifier.spage969en_US
dc.identifier.epage978en_US
dc.publisher.placeNetherlands-

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