File Download

There are no files associated with this item.

  Links for fulltext
     (May Require Subscription)
Supplementary

Article: An experimental gingivitis study to evaluate the clinical effects of a stannous fluoride dentifrice.

TitleAn experimental gingivitis study to evaluate the clinical effects of a stannous fluoride dentifrice.
Authors
Issue Date2004
PublisherQuintessence Publishing Co Ltd. The Journal's web site is located at http://www.quintessencepublishing.co.uk/catalog/product_info.php?cPath=3&products_id=239
Citation
Oral Health & Preventive Dentistry, 2004, v. 2 n. 4, p. 369-376 How to Cite?
Abstract
PURPOSE: A double blind, controlled, parallel group trial utilizing the experimental gingivitis model was performed on thirty young adults to evaluate the clinical effects of a 0.45% stannous fluoride dentifrice used as a slurry on dental biofilm formation and the development of gingivitis. MATERIAL AND METHODS: Following a thorough examination and oral prophylaxis procedures, subjects were randomly assigned to apply one of the following dentifrices twice daily over a three-week period: A) dentifrice slurry without active ingredients; B) 0.45% stannous fluoride gel; and C) Colgate Total dentifrice slurry (0.30% triclosan, 0.24% sodium fluoride, 2% copolymer). RESULTS: After three weeks, the stannous fluoride dentifrice significantly (p < 0.05) reduced gingivitis compared with the Colgate Total group by 39.7%. Gingival bleeding was also reduced relative to the Colgate Total group. This difference was statistically significant (P < 0.05). During the experimental period, the mean PII scores increased almost linearly in all three groups without yielding any statistically significant differences. CONCLUSIONS: The results of this clinical trial demonstrated that, over a three-week period, the application of a 0.45% SnF2 gel significantly inhibited the onset of gingivitis compared to Triclosan/sodium fluoride/copolymer (Colgate Total). However, neither stannous fluoride nor Triclosan/sodium fluoride/ copolymer (Colgate Total) possessed sufficient antimicrobial activity to suppress biofilm formation in the absence of regular oral hygiene practices.
Persistent Identifierhttp://hdl.handle.net/10722/154384
ISSN
2013 Impact Factor: 0.532
2013 SCImago Journal Rankings: 0.369

 

DC FieldValueLanguage
dc.contributor.authorLang, NPen_US
dc.contributor.authorAnton, Een_US
dc.contributor.authorGabriel, Yen_US
dc.contributor.authorSalvi, GEen_US
dc.contributor.authorPjetursson, BEen_US
dc.contributor.authorWinston, JLen_US
dc.contributor.authorHe, Ten_US
dc.date.accessioned2012-08-08T08:25:00Z-
dc.date.available2012-08-08T08:25:00Z-
dc.date.issued2004en_US
dc.identifier.citationOral Health & Preventive Dentistry, 2004, v. 2 n. 4, p. 369-376en_US
dc.identifier.issn1602-1622en_US
dc.identifier.urihttp://hdl.handle.net/10722/154384-
dc.description.abstractPURPOSE: A double blind, controlled, parallel group trial utilizing the experimental gingivitis model was performed on thirty young adults to evaluate the clinical effects of a 0.45% stannous fluoride dentifrice used as a slurry on dental biofilm formation and the development of gingivitis. MATERIAL AND METHODS: Following a thorough examination and oral prophylaxis procedures, subjects were randomly assigned to apply one of the following dentifrices twice daily over a three-week period: A) dentifrice slurry without active ingredients; B) 0.45% stannous fluoride gel; and C) Colgate Total dentifrice slurry (0.30% triclosan, 0.24% sodium fluoride, 2% copolymer). RESULTS: After three weeks, the stannous fluoride dentifrice significantly (p < 0.05) reduced gingivitis compared with the Colgate Total group by 39.7%. Gingival bleeding was also reduced relative to the Colgate Total group. This difference was statistically significant (P < 0.05). During the experimental period, the mean PII scores increased almost linearly in all three groups without yielding any statistically significant differences. CONCLUSIONS: The results of this clinical trial demonstrated that, over a three-week period, the application of a 0.45% SnF2 gel significantly inhibited the onset of gingivitis compared to Triclosan/sodium fluoride/copolymer (Colgate Total). However, neither stannous fluoride nor Triclosan/sodium fluoride/ copolymer (Colgate Total) possessed sufficient antimicrobial activity to suppress biofilm formation in the absence of regular oral hygiene practices.en_US
dc.languageengen_US
dc.publisherQuintessence Publishing Co Ltd. The Journal's web site is located at http://www.quintessencepublishing.co.uk/catalog/product_info.php?cPath=3&products_id=239en_US
dc.relation.ispartofOral health & preventive dentistryen_US
dc.subject.meshAdulten_US
dc.subject.meshComplex Mixtures - Therapeutic Useen_US
dc.subject.meshDental Plaque - Prevention & Controlen_US
dc.subject.meshDental Plaque Indexen_US
dc.subject.meshDentifrices - Therapeutic Useen_US
dc.subject.meshDouble-Blind Methoden_US
dc.subject.meshFemaleen_US
dc.subject.meshFluorides - Therapeutic Useen_US
dc.subject.meshGingivitis - Prevention & Controlen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshPeriodontal Indexen_US
dc.subject.meshSilicic Aciden_US
dc.subject.meshTin Fluorides - Therapeutic Useen_US
dc.subject.meshToothpastesen_US
dc.subject.meshTriclosan - Therapeutic Useen_US
dc.titleAn experimental gingivitis study to evaluate the clinical effects of a stannous fluoride dentifrice.en_US
dc.typeArticleen_US
dc.identifier.emailLang, NP:nplang@hkucc.hku.hken_US
dc.identifier.authorityLang, NP=rp00031en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid16296255en_US
dc.identifier.scopuseid_2-s2.0-33644631289en_US
dc.identifier.volume2en_US
dc.identifier.issue4en_US
dc.identifier.spage369en_US
dc.identifier.epage376en_US
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridLang, NP=7201577367en_US
dc.identifier.scopusauthoridAnton, E=12760912400en_US
dc.identifier.scopusauthoridGabriel, Y=12760793100en_US
dc.identifier.scopusauthoridSalvi, GE=35600695300en_US
dc.identifier.scopusauthoridPjetursson, BE=6506841442en_US
dc.identifier.scopusauthoridWinston, JL=7006607642en_US
dc.identifier.scopusauthoridHe, T=35315835300en_US

Export via OAI-PMH Interface in XML Formats


OR


Export to Other Non-XML Formats