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Article: The antimicrobial activity of a dentin conditioner combined with antibacterial agents

TitleThe antimicrobial activity of a dentin conditioner combined with antibacterial agents
Authors
Issue Date2005
PublisherOperative Dentistry. The Journal's web site is located at http://www.jopdent.org
Citation
Operative Dentistry, 2005, v. 30 n. 1, p. 75-82 How to Cite?
AbstractDental hand instruments are not efficient in removing all infected dentin when performing carious removal for minimal intervention techniques. The use of an antibacterial dentin conditioner may therefore be useful when restoring cavities that have residual carious dentin. Antibacterial agents - chlorhexidine hydrochloride, cetylpyridinium chloride, cetrimide, benzalkonium chloride and sodium hypochlorite, were added either to a dentin conditioner used for glass ionomer cements or distilled water at 1% concentration. Dentin conditioning solutions at pH 2.5, 4.9 and 7.7 were also prepared, along with 1% aqueous thymol. Using an agar diffusion test, 25 μl aliquots were examined for their inhibitory effects on three cariogenic bacteria. After 24 hours, an agar pellet was extracted adjacent to the agar well and placed on a second inoculated agar plate to observe sustained inhibitory effects, after which this procedure was repeated one more time. Antibacterial dentin conditioners showed significant inhibitory effect compared to the control over the three test periods (p<0.016). The combination of dentin conditioners with antibacterial agents significantly reduced the inhibitory effect compared to the antibacterial aqueous solutions (p<0.016). One-percent aqueous thymol showed no inhibitory effect against the test bacteria. The cetrimide-dentin conditioner showed the greatest inhibitory effect against all three test bacteria over the three experimental periods (p<0.016). The inhibitory effect of antibacterial agents was significantly reduced when combined with a dentin conditioner. Only the cetrimide-dentin conditioner combination produced significant inhibitory effects against all three test organisms. © Operative Dentistry, 2005.
Persistent Identifierhttp://hdl.handle.net/10722/154299
ISSN
2015 Impact Factor: 2.819
2015 SCImago Journal Rankings: 0.641
ISI Accession Number ID
References

 

DC FieldValueLanguage
dc.contributor.authorBotelho, MGen_US
dc.date.accessioned2012-08-08T08:24:28Z-
dc.date.available2012-08-08T08:24:28Z-
dc.date.issued2005en_US
dc.identifier.citationOperative Dentistry, 2005, v. 30 n. 1, p. 75-82en_US
dc.identifier.issn0361-7734en_US
dc.identifier.urihttp://hdl.handle.net/10722/154299-
dc.description.abstractDental hand instruments are not efficient in removing all infected dentin when performing carious removal for minimal intervention techniques. The use of an antibacterial dentin conditioner may therefore be useful when restoring cavities that have residual carious dentin. Antibacterial agents - chlorhexidine hydrochloride, cetylpyridinium chloride, cetrimide, benzalkonium chloride and sodium hypochlorite, were added either to a dentin conditioner used for glass ionomer cements or distilled water at 1% concentration. Dentin conditioning solutions at pH 2.5, 4.9 and 7.7 were also prepared, along with 1% aqueous thymol. Using an agar diffusion test, 25 μl aliquots were examined for their inhibitory effects on three cariogenic bacteria. After 24 hours, an agar pellet was extracted adjacent to the agar well and placed on a second inoculated agar plate to observe sustained inhibitory effects, after which this procedure was repeated one more time. Antibacterial dentin conditioners showed significant inhibitory effect compared to the control over the three test periods (p<0.016). The combination of dentin conditioners with antibacterial agents significantly reduced the inhibitory effect compared to the antibacterial aqueous solutions (p<0.016). One-percent aqueous thymol showed no inhibitory effect against the test bacteria. The cetrimide-dentin conditioner showed the greatest inhibitory effect against all three test bacteria over the three experimental periods (p<0.016). The inhibitory effect of antibacterial agents was significantly reduced when combined with a dentin conditioner. Only the cetrimide-dentin conditioner combination produced significant inhibitory effects against all three test organisms. © Operative Dentistry, 2005.en_US
dc.languageengen_US
dc.publisherOperative Dentistry. The Journal's web site is located at http://www.jopdent.orgen_US
dc.relation.ispartofOperative Dentistryen_US
dc.subject.meshAcid Etching, Dentalen_US
dc.subject.meshAcrylic Resins - Pharmacologyen_US
dc.subject.meshActinomyces - Drug Effectsen_US
dc.subject.meshAnalysis Of Varianceen_US
dc.subject.meshAnti-Infective Agents, Local - Pharmacologyen_US
dc.subject.meshBenzalkonium Compounds - Pharmacologyen_US
dc.subject.meshCetylpyridinium - Pharmacologyen_US
dc.subject.meshChlorhexidine - Pharmacologyen_US
dc.subject.meshDental Caries - Therapyen_US
dc.subject.meshDental Restoration, Permanent - Methodsen_US
dc.subject.meshDentin - Drug Effectsen_US
dc.subject.meshGlass Ionomer Cementsen_US
dc.subject.meshHydrogen-Ion Concentrationen_US
dc.subject.meshLactobacillus Casei - Drug Effectsen_US
dc.subject.meshMicrobial Sensitivity Testsen_US
dc.subject.meshSodium Hypochlorite - Pharmacologyen_US
dc.subject.meshStatistics, Nonparametricen_US
dc.subject.meshStreptococcus Mutans - Drug Effectsen_US
dc.subject.meshThymol - Pharmacologyen_US
dc.titleThe antimicrobial activity of a dentin conditioner combined with antibacterial agentsen_US
dc.typeArticleen_US
dc.identifier.emailBotelho, MG:botelho@hkucc.hku.hken_US
dc.identifier.authorityBotelho, MG=rp00033en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid15765961-
dc.identifier.scopuseid_2-s2.0-14844323191en_US
dc.identifier.hkuros102070-
dc.relation.referenceshttp://www.scopus.com/mlt/select.url?eid=2-s2.0-14844323191&selection=ref&src=s&origin=recordpageen_US
dc.identifier.volume30en_US
dc.identifier.issue1en_US
dc.identifier.spage75en_US
dc.identifier.epage82en_US
dc.identifier.isiWOS:000226843500012-
dc.publisher.placeUnited Statesen_US
dc.identifier.scopusauthoridBotelho, MG=7005751169en_US

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