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Article: Antimycotic agents in oral candidosis: an overview: 2. Treatment of oral candidosis.

TitleAntimycotic agents in oral candidosis: an overview: 2. Treatment of oral candidosis.
Authors
Issue Date2000
PublisherGeorge Warman Publications Ltd. The Journal's web site is located at http://www.dental-update.co.uk/
Citation
Dental Update, 2000, v. 27 n. 4, p. 165-170, 172 How to Cite?
AbstractAs both humans and fungi are eukaryotic organisms, antifungal agents affect their cellular metabolism. Thus, a relatively few antifungals with minimal toxicity and side-effects are available compared with a plethora of antibacterials. These agents currently prescribed in dentistry belong to two major groups, the polyenes (nystatin and amphotericin B) and the azoles (imidazoles and triazoles). A newly recognized phenomenon known as the post-antifungal effect implies that antifungals, even at sub-therapeutic concentrations, may suppress the virulent attributes of yeasts, especially intra-orally where topical drug levels fluctuate dramatically during dosing intervals.
Persistent Identifierhttp://hdl.handle.net/10722/154105
ISSN
2015 SCImago Journal Rankings: 0.202

 

DC FieldValueLanguage
dc.contributor.authorEllepola, ANen_US
dc.contributor.authorSamaranayake, LPen_US
dc.date.accessioned2012-08-08T08:23:17Z-
dc.date.available2012-08-08T08:23:17Z-
dc.date.issued2000en_US
dc.identifier.citationDental Update, 2000, v. 27 n. 4, p. 165-170, 172en_US
dc.identifier.issn0305-5000en_US
dc.identifier.urihttp://hdl.handle.net/10722/154105-
dc.description.abstractAs both humans and fungi are eukaryotic organisms, antifungal agents affect their cellular metabolism. Thus, a relatively few antifungals with minimal toxicity and side-effects are available compared with a plethora of antibacterials. These agents currently prescribed in dentistry belong to two major groups, the polyenes (nystatin and amphotericin B) and the azoles (imidazoles and triazoles). A newly recognized phenomenon known as the post-antifungal effect implies that antifungals, even at sub-therapeutic concentrations, may suppress the virulent attributes of yeasts, especially intra-orally where topical drug levels fluctuate dramatically during dosing intervals.en_US
dc.languageengen_US
dc.publisherGeorge Warman Publications Ltd. The Journal's web site is located at http://www.dental-update.co.uk/en_US
dc.relation.ispartofDental updateen_US
dc.subject.meshAmphotericin B - Administration & Dosage - Therapeutic Useen_US
dc.subject.meshAntifungal Agents - Administration & Dosage - Adverse Effects - Classification - Therapeutic Useen_US
dc.subject.meshCandida - Drug Effects - Growth & Development - Pathogenicityen_US
dc.subject.meshCandidiasis, Oral - Drug Therapyen_US
dc.subject.meshClotrimazole - Administration & Dosage - Therapeutic Useen_US
dc.subject.meshDrug Interactionsen_US
dc.subject.meshDrug Resistance, Microbialen_US
dc.subject.meshFluconazole - Administration & Dosage - Therapeutic Useen_US
dc.subject.meshHumansen_US
dc.subject.meshItraconazole - Administration & Dosage - Therapeutic Useen_US
dc.subject.meshKetoconazole - Administration & Dosage - Therapeutic Useen_US
dc.subject.meshMiconazole - Administration & Dosage - Therapeutic Useen_US
dc.subject.meshNystatin - Administration & Dosage - Therapeutic Useen_US
dc.subject.meshVirulence - Drug Effectsen_US
dc.titleAntimycotic agents in oral candidosis: an overview: 2. Treatment of oral candidosis.en_US
dc.typeArticleen_US
dc.identifier.emailSamaranayake, LP:lakshman@hku.hken_US
dc.identifier.authoritySamaranayake, LP=rp00023en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid11218451-
dc.identifier.scopuseid_2-s2.0-0034189268en_US
dc.identifier.hkuros48507-
dc.identifier.volume27en_US
dc.identifier.issue4en_US
dc.identifier.spage165en_US
dc.identifier.epage170, 172en_US
dc.publisher.placeUnited Kingdomen_US
dc.identifier.scopusauthoridEllepola, AN=6604060863en_US
dc.identifier.scopusauthoridSamaranayake, LP=7102761002en_US

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