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Article: Clinical trials on therapies for peri-implant infections.

TitleClinical trials on therapies for peri-implant infections.
Authors
Issue Date1997
Citation
Annals Of Periodontology / The American Academy Of Periodontology, 1997, v. 2 n. 1, p. 343-356 How to Cite?
AbstractPeri-implant infections are pathological conditions which are normally localized in the soft tissues surrounding an oral implant. They may range from a rather localized mucositis lesion reflecting the host response to a bacterial challenge to a more advanced lesion "termed peri-implantitis" when previously osseointegrated oral implants have been partially disintegrated; i.e. have lost alveolar bone around the implant. Usually these lesions start as a result of plaque accumulation and show similar progression as observed around teeth. Muscositis seems to be a prerequisite for the following peri-implantitis. However, the factors involving the transition to a more advanced lesion are still not known. Logically, the therapy for peri-implant infection has to be related to antibacterial treatment prior to the attempt to surgically regenerate peri-implant alveolar bone lost as a result of the infection. In order to diagnose these lesions at an early stage frequent assessments of clinical parameters are needed during maintenance therapy. The anti-infective treatment may intercept the development of the lesion. Following mechanical debridement of plaque deposits the application of efficacious antiseptics (chlorhexidine) is a necessity. Following this, antibiotics may cumulatively be applied to control the infection. Only a few longitudinal studies have documented the efficacy of such treatment regimens, and controls have generally not been available for ethical reasons. In regenerating the lost jaw bone only case reports are available today. Controlled animal studies will have to be performed to document the possibility of re-osseointegration and the factors influencing predictability.
Persistent Identifierhttp://hdl.handle.net/10722/153990
ISSN
2006 SCImago Journal Rankings: 3.127

 

DC FieldValueLanguage
dc.contributor.authorLang, NPen_US
dc.contributor.authorMombelli, Aen_US
dc.contributor.authorTonetti, MSen_US
dc.contributor.authorBrägger, Uen_US
dc.contributor.authorHämmerle, CHen_US
dc.date.accessioned2012-08-08T08:22:41Z-
dc.date.available2012-08-08T08:22:41Z-
dc.date.issued1997en_US
dc.identifier.citationAnnals Of Periodontology / The American Academy Of Periodontology, 1997, v. 2 n. 1, p. 343-356en_US
dc.identifier.issn1553-0841en_US
dc.identifier.urihttp://hdl.handle.net/10722/153990-
dc.description.abstractPeri-implant infections are pathological conditions which are normally localized in the soft tissues surrounding an oral implant. They may range from a rather localized mucositis lesion reflecting the host response to a bacterial challenge to a more advanced lesion "termed peri-implantitis" when previously osseointegrated oral implants have been partially disintegrated; i.e. have lost alveolar bone around the implant. Usually these lesions start as a result of plaque accumulation and show similar progression as observed around teeth. Muscositis seems to be a prerequisite for the following peri-implantitis. However, the factors involving the transition to a more advanced lesion are still not known. Logically, the therapy for peri-implant infection has to be related to antibacterial treatment prior to the attempt to surgically regenerate peri-implant alveolar bone lost as a result of the infection. In order to diagnose these lesions at an early stage frequent assessments of clinical parameters are needed during maintenance therapy. The anti-infective treatment may intercept the development of the lesion. Following mechanical debridement of plaque deposits the application of efficacious antiseptics (chlorhexidine) is a necessity. Following this, antibiotics may cumulatively be applied to control the infection. Only a few longitudinal studies have documented the efficacy of such treatment regimens, and controls have generally not been available for ethical reasons. In regenerating the lost jaw bone only case reports are available today. Controlled animal studies will have to be performed to document the possibility of re-osseointegration and the factors influencing predictability.en_US
dc.languageengen_US
dc.relation.ispartofAnnals of periodontology / the American Academy of Periodontologyen_US
dc.subject.meshAnimalsen_US
dc.subject.meshClinical Trials As Topicen_US
dc.subject.meshDental Implantation, Endosseous - Adverse Effectsen_US
dc.subject.meshDental Implants - Adverse Effects - Microbiologyen_US
dc.subject.meshDental Restoration Failureen_US
dc.subject.meshHumansen_US
dc.subject.meshPatient Care Planningen_US
dc.subject.meshPeriodontitis - Etiologyen_US
dc.subject.meshProsthesis-Related Infections - Etiology - Therapyen_US
dc.titleClinical trials on therapies for peri-implant infections.en_US
dc.typeArticleen_US
dc.identifier.emailLang, NP:nplang@hkucc.hku.hken_US
dc.identifier.authorityLang, NP=rp00031en_US
dc.description.naturelink_to_subscribed_fulltexten_US
dc.identifier.pmid9151566-
dc.identifier.scopuseid_2-s2.0-0031087425en_US
dc.identifier.volume2en_US
dc.identifier.issue1en_US
dc.identifier.spage343en_US
dc.identifier.epage356en_US
dc.identifier.scopusauthoridLang, NP=7201577367en_US
dc.identifier.scopusauthoridMombelli, A=7006180872en_US
dc.identifier.scopusauthoridTonetti, MS=35602248900en_US
dc.identifier.scopusauthoridBrägger, U=7005538598en_US
dc.identifier.scopusauthoridHämmerle, CH=7005331848en_US

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