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  Patent History
  • Application
    US 12/502548 2009-07-14
  • Publication
    US 20100008925 2010-01-14
  • Granted
    US 7960338 2011-06-14
Supplementary

granted patent: Methods And Compositions For Treatment Of Endotoxin-Mediated Pro-Inflammatory Responses

TitleMethods And Compositions For Treatment Of Endotoxin-Mediated Pro-Inflammatory Responses
Granted PatentUS 7960338
Granted Date2011-06-14
Priority Date2009-07-14 US 12/502548
2008-07-14 US 12/080558P
Inventors
Issue Date2011
Citation
US Patent 7960338. Washington, DC: US Patent and Trademark Office (USPTO), 2011 How to Cite?
AbstractBacterial Lipopolysaccharide (Lps) In Systemic Circulation Triggers Deleterious Super-Inflammatory Response, Which Is Key Pathogenesis Of Many Disorders Like Gram-Negative Sepsis And Necrotizing Enterocolitis. No Effective Therapeutic Interventions Are Currently Available For Protection Of Patients Against Mortality. Disclosed Are Methods And Therapeutic Agents That Ablate The Biological Toxicity Of Lps In Circulation (Integrin Peptide), And Abrogate Leukocyte Infiltration Into Lung And Liver And Suppress Adhesion Molecule Expression (Integrin Peptide And Anti-Cd18 [Beta]A Scfv). These Therapeutic Agents Can Be Used Alone, Or In Combination For Treatment Of Endotoxin-Mediated Pro-Inflammatory Responses, Particularly In Cases Of Acute Sepsis And Necrotizing Enterocolitis.
Persistent Identifierhttp://hdl.handle.net/10722/142182
References

 

DC FieldValueLanguage
dc.date.accessioned2011-10-19T06:34:07Z-
dc.date.available2011-10-19T06:34:07Z-
dc.date.issued2011-
dc.identifier.citationUS Patent 7960338. Washington, DC: US Patent and Trademark Office (USPTO), 2011en_HK
dc.identifier.urihttp://hdl.handle.net/10722/142182-
dc.description.abstractBacterial Lipopolysaccharide (Lps) In Systemic Circulation Triggers Deleterious Super-Inflammatory Response, Which Is Key Pathogenesis Of Many Disorders Like Gram-Negative Sepsis And Necrotizing Enterocolitis. No Effective Therapeutic Interventions Are Currently Available For Protection Of Patients Against Mortality. Disclosed Are Methods And Therapeutic Agents That Ablate The Biological Toxicity Of Lps In Circulation (Integrin Peptide), And Abrogate Leukocyte Infiltration Into Lung And Liver And Suppress Adhesion Molecule Expression (Integrin Peptide And Anti-Cd18 [Beta]A Scfv). These Therapeutic Agents Can Be Used Alone, Or In Combination For Treatment Of Endotoxin-Mediated Pro-Inflammatory Responses, Particularly In Cases Of Acute Sepsis And Necrotizing Enterocolitis.en_HK
dc.rightsCreative Commons: Attribution 3.0 Hong Kong License For Public Patent Documents-
dc.titleMethods And Compositions For Treatment Of Endotoxin-Mediated Pro-Inflammatory Responsesen_HK
dc.typePatenten_US
dc.identifier.emailFan, Sheung Tat:stfan@hku.hken_US
dc.identifier.emailLuk, John Moon Ching:jmluk@hkucc.hku.hken_US
dc.identifier.emailPoon, Ronnie Tung Ping:poontp@hkucc.hku.hken_US
dc.identifier.emailWong, Kwong Fai:tonywkf@hku.hken_US
dc.identifier.authorityFan, Sheung Tat=rp00355en_US
dc.identifier.authorityLuk, John Moon Ching=rp00349en_US
dc.identifier.authorityPoon, Ronnie Tung Ping=rp00446en_US
dc.description.naturepublished_or_final_version-
dc.contributor.inventorLuk, John Moon Chingen_US
dc.contributor.inventorWong, Kwong Faien_US
dc.contributor.inventorPoon, Ronnie Tung Pingen_US
dc.contributor.inventorFan, Sheung Taten_US
patents.identifier.applicationUS 12/502548en_HK
patents.identifier.grantedUS 7960338en_HK
patents.description.assigneeUniv Hong Kong [Hk]en_HK
patents.description.countryUnited States of Americaen_HK
patents.date.publication2010-01-14en_HK
patents.date.granted2011-06-14en_HK
dc.relation.referencesUS 2004127416 (A1) 2004-07-01en_HK
dc.relation.referencesWO 2004045542 (A2) 2004-06-03en_HK
dc.relation.referencesWO 2004045542 (A3) 2004-10-21en_HK
dc.relation.referencesWO 2004066914 (A2) 2004-08-12en_HK
dc.relation.referencesWO 2004066914 (A3) 2004-09-23en_HK
patents.identifier.hkutechidSurg-2007-00270-1en_US
patents.date.application2009-07-14en_HK
patents.date.priority2009-07-14 US 12/502548en_HK
patents.date.priority2008-07-14 US 12/080558Pen_HK
patents.description.ccUSen_HK
patents.identifier.publicationUS 20100008925en_HK
patents.relation.familyCN 102239179 (A) 2011-11-09en_HK
patents.relation.familyUS 2010008925 (A1) 2010-01-14en_HK
patents.relation.familyUS 7960338 (B2) 2011-06-14en_HK
patents.relation.familyWO 2010006508 (A1) 2010-01-21en_HK
patents.description.kindB2en_HK
patents.typePatent_granteden_HK

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