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Article: Chemical and molecular characterization of Hong Dangshen, a unique medicinal material for diarrhea in Hong Kong

TitleChemical and molecular characterization of Hong Dangshen, a unique medicinal material for diarrhea in Hong Kong
香港特有止瀉中藥材紅黨參的化學和分子生物學鑒定(英文)
Authors
KeywordsRadix Codonopsis Praeparata Halloysita Rubra
Codonopsis pilosula var. modesta
HPLC
5S rRNA gene spacer
Halloysitum Rubrum
Issue Date2007
PublisherPeking University, School of Pharmaceutical Sciences. The Journal's website is located at http://www.jcps.ac.cn
Citation
中國藥學(英文版), 2007, v. 16 n. 3, p. 202-207 How to Cite?
Journal of Chinese Pharmaceutical Sciences, 2007, v. 16 n. 13, p. 202-207 How to Cite?
AbstractAim: To investigate the plant origin and the identity of the red substance on the surface of Hong Dangshen, a unique medicinal material for diarrhea in Hong Kong. Methods The HPLC fingerprints and 5S rRNA gene spacer sequences of Hong Dangshen were obtained and compared with those of genuine species of Radix Codonopsis. The X-ray diffraction spectrum of the red substance was analyzed and compared with that of Halloysitum Rubrum. Results Hong Dangshen showed very similar HPLC fingerprints to the Codonopsis species and the highest similarity to Codonopsis pilosula var. modesta in terms of 5S rRNA gene spacer sequences. The X-ray diffraction spectrum of the red substance was consistent with that of Halloysitum Rubrum. Conclusion The source plant of Hong Dangshen was suggested to be Codonopsis pilosula var. modesta, one of the genuine original plants of Radix Codonopsis (Dangshen) in the China Pharmacopoeia (2005 edition). The red substance on the surface of Hong Dangshen was indicated to be Halloysitum Rubrum, a traditional medicinal mineral for chronic diarrhea. Our data suggest that Hong Dangshen is derived from the roots of Codonopsis pilosula var. modesta which has been processed with Halloysitum Rubrum, and the name is suggested to be Radix Codonopsis Praeparata Halloysita Rubra. 目的鑒定香港特有止瀉中藥材紅黨參的基源植物和表面紅色物質。方法將紅黨參的5SrRNA基因間隔區序列和HPLC色譜指紋譜與正品黨參5SrRNA基因間隔區序列和HPLC色譜指紋譜進行比較研究;將紅黨參表面紅色物質的X-衍射光譜與中藥赤石脂X-衍射光譜進行比較研究。結果紅黨參的HPLC色譜指紋譜和黨參藥材具有相同的特征色譜峰;紅黨參的5SrRNA基因間隔區序列與黨參正品之一的素花黨參(Codonopsis pilosula var.modesta)的5SrRNA基因間隔區序列最為相似;紅色物質的X-衍射光譜與中藥赤石脂X-衍射光譜完全相同。結論紅黨參的基源是素花黨參(Codonopsis pilosula var.modesta)的根,紅黨參表面的紅色物質是傳統中藥赤石脂(Halloysitum Rubrum)。紅黨參是素花黨參根用中藥赤石脂炮制而成,科學名可定為Radix Codonopsis Praeparata Halloysita Rubra。
Persistent Identifierhttp://hdl.handle.net/10722/138118
ISSN
2015 SCImago Journal Rankings: 0.184

 

DC FieldValueLanguage
dc.contributor.authorZhang, YBen_US
dc.contributor.authorJiang, RWen_US
dc.contributor.authorLi, SLen_US
dc.contributor.authorQiao, CFen_US
dc.contributor.authorHan, QBen_US
dc.contributor.authorXu, HXen_US
dc.contributor.authorWong, KLen_US
dc.contributor.authorBut, PPHen_US
dc.contributor.authorShaw, PC-
dc.date.accessioned2011-08-26T14:41:01Z-
dc.date.available2011-08-26T14:41:01Z-
dc.date.issued2007en_US
dc.identifier.citation中國藥學(英文版), 2007, v. 16 n. 3, p. 202-207zh_HK
dc.identifier.citationJournal of Chinese Pharmaceutical Sciences, 2007, v. 16 n. 13, p. 202-207-
dc.identifier.issn1003-1057-
dc.identifier.urihttp://hdl.handle.net/10722/138118-
dc.description.abstractAim: To investigate the plant origin and the identity of the red substance on the surface of Hong Dangshen, a unique medicinal material for diarrhea in Hong Kong. Methods The HPLC fingerprints and 5S rRNA gene spacer sequences of Hong Dangshen were obtained and compared with those of genuine species of Radix Codonopsis. The X-ray diffraction spectrum of the red substance was analyzed and compared with that of Halloysitum Rubrum. Results Hong Dangshen showed very similar HPLC fingerprints to the Codonopsis species and the highest similarity to Codonopsis pilosula var. modesta in terms of 5S rRNA gene spacer sequences. The X-ray diffraction spectrum of the red substance was consistent with that of Halloysitum Rubrum. Conclusion The source plant of Hong Dangshen was suggested to be Codonopsis pilosula var. modesta, one of the genuine original plants of Radix Codonopsis (Dangshen) in the China Pharmacopoeia (2005 edition). The red substance on the surface of Hong Dangshen was indicated to be Halloysitum Rubrum, a traditional medicinal mineral for chronic diarrhea. Our data suggest that Hong Dangshen is derived from the roots of Codonopsis pilosula var. modesta which has been processed with Halloysitum Rubrum, and the name is suggested to be Radix Codonopsis Praeparata Halloysita Rubra. 目的鑒定香港特有止瀉中藥材紅黨參的基源植物和表面紅色物質。方法將紅黨參的5SrRNA基因間隔區序列和HPLC色譜指紋譜與正品黨參5SrRNA基因間隔區序列和HPLC色譜指紋譜進行比較研究;將紅黨參表面紅色物質的X-衍射光譜與中藥赤石脂X-衍射光譜進行比較研究。結果紅黨參的HPLC色譜指紋譜和黨參藥材具有相同的特征色譜峰;紅黨參的5SrRNA基因間隔區序列與黨參正品之一的素花黨參(Codonopsis pilosula var.modesta)的5SrRNA基因間隔區序列最為相似;紅色物質的X-衍射光譜與中藥赤石脂X-衍射光譜完全相同。結論紅黨參的基源是素花黨參(Codonopsis pilosula var.modesta)的根,紅黨參表面的紅色物質是傳統中藥赤石脂(Halloysitum Rubrum)。紅黨參是素花黨參根用中藥赤石脂炮制而成,科學名可定為Radix Codonopsis Praeparata Halloysita Rubra。zh_HK
dc.languageengen_US
dc.publisherPeking University, School of Pharmaceutical Sciences. The Journal's website is located at http://www.jcps.ac.cn-
dc.relation.ispartof中國藥學(英文版)zh_HK
dc.relation.ispartofJournal of Chinese Pharmaceutical Sciences-
dc.subjectRadix Codonopsis Praeparata Halloysita Rubra-
dc.subjectCodonopsis pilosula var. modesta-
dc.subjectHPLC-
dc.subject5S rRNA gene spacer-
dc.subjectHalloysitum Rubrum-
dc.titleChemical and molecular characterization of Hong Dangshen, a unique medicinal material for diarrhea in Hong Kongen_US
dc.title香港特有止瀉中藥材紅黨參的化學和分子生物學鑒定(英文)zh_HK
dc.typeArticleen_US
dc.identifier.openurlhttp://library.hku.hk:4550/resserv?sid=HKU:IR&issn=1003-1057&volume=16&issue=13&spage=202&epage=207&date=2007&atitle=Chemical+and+molecular+characterization+of+Hong+Dangshen,+a+unique+medicinal+material+for+diarrhea+in+Hong+Kong-
dc.identifier.emailZhang, YB: ybzhang@hku.hken_US
dc.identifier.authorityZhang, YB=rp01410en_US
dc.identifier.hkuros145919en_US
dc.identifier.volume16en_US
dc.identifier.issue3en_US
dc.identifier.spage202en_US
dc.identifier.epage207en_US

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