Collection View Count

Geo Map
Region#
AS - Asia6233
EU - Europe2529
NA - North America2034
HKU - The University of Hong Kong1601
OC - Oceania35
AF - Africa19
SA - South America8
UND - Undefined7
Total12466
Country#
CN - China5478
US - United States1980
HKU - The University of Hong Kong1601
FR - France908
GB - United Kingdom825
HK - Hong Kong420
DE - Germany338
RU - Russia213
KR - Republic of Korea174
PL - Poland122
OTH - Others407
Total12466
City#
The University of Hong Kong1601
Beijing1378
Shenzhen1153
Nanjing964
Clarks Summit604
Ashburn487
Wuhan261
Shengping236
Central District202
Emeryville192
Others5388
Total12466
Identification of a novel pathogenic peptide of mouse thyroid peroxidase (MTPO) and ascertainment of immune tolerance in a transgenic model that ovderexpresses MTPO in the thymus48
Rapid induction of preproendothelin-1 mRNA in both astrocytes and cerebral endothelial cells of hypoxic-ischemic mouse brain59
Catalase and peroxiredoxin 5 protect Xenopus embryos against alcohol-induced ocular anomalies48
Inhibition of 12-lipoxygenase induced apoptosis in human gastric cancer cells44
Insulin down-regulates MTP gene transcription through ras independent MAPKerk cascade in HepG2 cells47
Overexpression of dominant-negative osmotic respose element binding protein (OREBP) in kidney resulting in polydipsic and polyuric phenotypes56
Interaction between the polyol pathway and non-enzymatic glycation on aortic smooth muscle cell migration and monocyte adhesion in a transgenic mouse model46
Interaction between non-enzymatic glycation and the polyol pathway on mesangial cell gene expression in an aldose reductase transgenic mouse model55
Pseudolaric acid B as a new class of microtubule destabilizing agent and an effective anti-tumor compound in vivo43
Diabetic nephropathy is associated with the Z-2 microsatellite allele of the aldose reductase gene in Chinese subjects with Type 2 diabetes34
Down-regulation of XIAP associated factor 1 (XAF1) through Hsf-1 binding in the promoter region66
The effects of sorbitol dehydrogenase deficiency on nerve conduction in experimental diabetic mice35
Identification and characterization of a novel cellular protein targeted by HTLV-1 Tax37
Characterization of a mutation that causes sorbitol dehydrogenase deficiency in mouse42
The transgenic/knockout mouse models for diabetic neuropathy44
A novel glioblastoma cancer gene therapy using AAV-mediated delivery of human TERT C-terminal polypeptide52
Molecular mechanisms of alcohol-induced microcephaly in xenopus embryos: oxidative stress mediated suppression of Pax-6 gene48
The potential of using Proteomic technology as a tool to analyze arsenic-induced vascular diseases43
Molecular approach to understand the regulation and function of endothelin-133
The adeno-associated virus plus adenovirus cocktail vector system produces high gene transduction efficiency and low immuno-response in rats54
Serum markers of hepatitis B virus infected liver inflammation: A proteomic sutdy57
Nonsteroidal Anti-Inflammatory Drugs Inhibit Human Telomerase Reverse Transcriptase (hTERT) in Gastric and Colon Cancer53
The expression patterns of p75 and zebrin II mrnas in the developing rat cerebellum40
rAAV-mediated long-term expression of endostatin significantly inhibits the progression of HCC80
Up-regulation of aldose reductase activity in cultured mesangial cells overexpressing human aldose reductase gene is associated with increased TGF-beta1 and collagen IV expression49
Endothelin-1 expression in the central and peripheral nervous system of transgenic mice49
Cyclooxygenase-2 Gene Disruption Enhances Gastric Inflammation but Inhibits Gastric Epithelial Proliferation Induced by H. pylori Infection59
Specific cyclooxygenase-2 (COX-2) inhibitor induce apoptosis in gastric cancer cells50
Identification and characterization of multiple osmotic response elements in the human aldose reductase gene46
Osmotic and oxidative stress in diabetic cataract49
Expression of GAP-43 in regenerating retinal ganglion cells following intravitreal transplanation of a short piece of peripheral nerve and replacement of the optic nerve with a long segment of peripheral nerve graft48
Survival effects of endothelin-1 on astrocytes during hypoxic/ischaemic injury involve ERK pathway38
The use of transgenic mouse models to understand the etiology of diabetic complications38
Enchanced expression of intestinal microsomal triglyceride transfer protein in zucker diabetic fatty rats, the role of oleate and growth hormones50
Restoration of XAF1 expression inhibits gastric and colonic tumorigenesis in vivo54
An over-expressed endothelin-1 transgenic mouse model for diabetic retinopathy study46
Inhibition of tumour promoter-induced activator protein 1 activation and cell transformation by a specific COX-2 inhibitor, SC23644
Molecular cloning and characterization of chondroitin 6-sulfotransferase (c6st) in crush-injured rat sciatic nerves57
Aging is associated with high cardiovascular risk in hypertensive patients60
Interaction between the polyol pathway and non-enzymatic glycation on aortic smooth muscle cell mirgration and moncyte adhesion in a transgenic mouse model69
Transgenic mice overexpressing endothelin-1 in astrocytes display greater infarct size and more severe neurological deficit after transient focal cerebral ischemia52
Proteomics analysis in transgenic mice over-expressing endothelin-1 in astrocytes after transient focal cerebral ischemia (Poster presentation)50
Development of novel therapies for liver cancer43
Novel cellular proteins targeted by HTLV-1 Tax54
Characterisation transgenic mice with the over-expression of endothelin-1 in endothelial cells as a model for experimental ischemic stroke53
Role of endothelin-1 in glial cell proliferation and apoptosis in retina of db/db mice49
Peripheral neuropathy in mice lacking the sodium/myo-inositol co-transporter gene43
Study on the role of sodium/myo-inositol co-transporter gene on neuromuscular disordeer55
Inhibition of anchorage-independent cell growth and activator protein-1 activation by specific COX-2 inhibitor61
ET-1 over-expression exacerbates reperfusion brain injury induced by transient focal cerebral ischemia in mice51
Endothelin-1 overexpression leads to blood-brain barrier disruption, more brain edema and increased aquaporin 4 expression in astrocytic processes after experimental stroke51
Antioxidant enzymes and ascorbic acid protects Xenopus laevis embryos against alcohol-induced neural injury61
Endothelin-1 mediated signaling for increased blood-brain barrier breakdown and infarct after transient focal cerebral ischemia63
Aldose reductase-deficient mice are alleviated from the depletion of GSH in the peripheral nerve and MNCV deficit associated with diabetes89
Specific COX-2 inhibitor suppresses anchorage-independent cell growth through AP-1/MAPK pathway in gastric cancer50
Treatment of Human and Rat Hepatocellular Carcinomas by Long Term Expression of rAAV-Mediated Transfer of Human TERTC27 Polypeptide54
Possible role of endothelin-1 during hypoxic/ischemic brain injury33
FHL2 as a co-factor of XAF1 in the induction of apoptosis72
Targeting survivin induced apoptosis and sensitized gastric and colon cancer cells to chemotherapy60
Blocking the polyol pathway protects diabetic mice against hypertriglyceridemia56
Gene regulaiton of aldose reductase and alterations in diabetic neuropathy35
Novel HCC gene therapy by rAAV-mediated transfer of human TERTC27 polypeptide in human and rat hepatocellular carcinoma (Abstract)83
Contribution of polyol pathway to diabetes-induced oxidative stress75
Spatiotemporal expression of chondroitin 6-sulfotransferase (C6ST) in regeneration of crush-injured sciatic nerves of adult rats52
The upregulation of GAP-43 is not sufficient to induce regeneration of retinal axons into a distally grafted peripheral nerve55
Hypermethylation Status Around Exon 1 of XIAP-Associated Factor 1 in Human Gastric and Colon Cancer Cell Lines44
Identify the potential roles of SMIT-1 in bone formation44
Sulindac metabolites induces XAF1 expression byinhibition of extracellular signal-regulated kinase 1/2phosphorylation in human gastric cancer cells50
Functional characterization of EFA6 in glioblastoma carcinogenesis34
Novel non-invasive approach to study the pathogenesis of chronic diabetic neuropathy58
Endothelin-1 over-expression leads to blood-brain barrier disruption resulting in increased infarct and edema after focal ischemia44
Transgenic mice of overexpressing a dominant negative form of OREBP developed congenital cataract44
Influence of peripheral nerve grafts on the expression of GAP-43 regenerating retinal ganglion cells in adult hamster58
Feedback inhibition of redox-responsive transcription factors Yap1p and Skn7p in Saccharomyes cerevisiae by peroxiredoxins Tsa1p and Tsa2p70
Stimulation of transferrin receptor expression by enhanced heme biosynthesis in murine erythroleukemia cells46
Expression of hepatocyte growth factor, C-Met, in sex hormone-induced prostate carcinogenesis in Noble rats49
Age is a strong cardiovascular risk factor in hypertensive patients80
Identification and characterization of a novel transcription factor LZIP as a binding partner and transformation confactor of hepatitis C virus core protein54
Genetic analysis of polyol pathway in sugar cateract48
Cold inducible RNA binding protein is essential for early embryonic development and neurogenesis in Xenopus Laevis63
ET-1 over-expression exacerbates reperfusion brain injury induced by transient focal cerebral ischemia in mice (poster presentation)45
Antisense Targeting Protein Kinase C Alpha Inhibit Gastric Carcinogenesis in Vivo41
Identification and characterization of mouse testin cDNA75
The Involvement of phosphatidylinositol-3 kinase signaling in neurogenesis during Xenopus embryonic development36
Down-regulation of transforming growth factor-b (TGF-b) receptors I and II during sex hormone-induced prostate carcinogenesis in the Noble rat38
Enhanced expression of gap-43 in retinal ganglion cells by an intravitreous peripheral nerve graft after intraorbital axotomy in hamsters60
Age is the strongest predictor of systolic blood pressure in hypertensive patients58
Expression of TrkB and TrkC as parasagittal bands in the cerebellum during development39
Regulation and signalling pathway of aldose reductase, betaine transporter, myo-inositol transporter genes expression by hyperosmolality41
HTLV-I oncogenesis and mitotic checkpoint52
Aldose reductase-deficient mice with diabetes are protected from the motor nerve conduction velocity deficit and axonal atrophy63
Correlation between the single-site CpG mutationwithin the gene promoter and the expression silencingof XIAP-Associated Factor 1 (XAF1) in human coloncancer cell lines92
The Expression of Secretin in the Mouse Embryonic Development61
Characterization of endothelin-1 gene manipulated mice for ischemic stroke, a leading cause of death and disability36
Characterization of the Xenopus homologue of ARL-4 during embryonic development55
Endothelin-1 leads to increased necrotic cell density in the brain after transient focal cerebral ischemia53
Interaction between the polyol pathway and non-enzymatic glycation on aortic smooth muscle cell migration and monocyte adhesion in a transgenic mouse model64
Transgenic mouse model to study polyol pathway in sugar cateract68
HTLV-I Tax and spindle assembly checkpoint41
The expression of growth associated protein and neural regeneration in the mammalian CNS40
Effect of hydroxycamptothecin and arsenic trioxide on expression of IAP-family genes in gastric and colon cancer cells58
Possible roles of endothelin-1 in astrocytes during hypoxic/ischemic brain injury46
Mice without eNOS or nNOS are not protected from the Diabetic Sexual Dysfunction40
Generation of osmotic response element binding protein (OREBP) knockout mice33
Macrophage migration inhibitory factor released by monocytes after co-culture with Helicobacter pylori stimulates proliferation of gasric epithelial cells51
The -258 G-A variant of the glucokinase gene hepatic promotor is associated with higher insulin scientivity60
Over-express endothelin-1 in astrocyte lead to increased brain damage and altered cytokine expression after cerebrl ischemia65
Idenfication of a novel pathogenic peptide of mouse thyroid perxidase (TPO) and ascertainment of immune tolerance in a transgenic model that overexpresses in TPO in the thymus.35
The use of the cre/loxP site-specific DNA recombination system to study endothelin-1 function62
Age is associated with high cardiovascular risk in hypertensive patients45
Gene Therapy for Colon Cancer Using Adeno-associated Virus Mediated Survivin Mutant45
Truncated α1-antitrypsin as an infection biomarker for Severe Acute Respiratory Syndrome (SARS)44
Bilirubin upregulates interleukin-6 expression in endothelia cells45
Symposium on Regulation of cerebrovascular blood flow and stroke38
Over-expression of endothelin-1 in astrocytes leads to blood-brain barrier disruption, increased infarct, brain edema and more severe neurological deficits after experimental stroke51
Macrophage Migration Inhibitory Factor Released by Monocytes after Co-Culture with Helicobacter pylori Increases Proliferation of Gastric Epithelial Cells60
The role of poly(ADP-ribose) polymerase in cataract development52
Interferon-β-induced expression of XAF1 requires phosphorylation of STAT1 and a sequential activation of protein kinase C and JNK in colon cancer349
Increased 6-sulfated chondroitins correlate with upregulated expression of chondroitin 6-transferase mRNA in post-crush sciatic nerves of adult rats.49
Inhibition of SARS-associated coronvirus infection and replication by siRNA35
Overexpression of dominant-negative osmotic response element binding protein (OREBP) in kidney resulting in polydipsic and polyuric phenotype55
Characterization of the antineurogenic element in the 3' UTR of the XGATA-1b transcript50
Increased serum levels and epithelial expression of macrophage migration inhibitory factor in gastric cancer56
Specific COX-2 inhibitor suppresses NF-kB activation by inhibition of RelA/p65 nuclear translocation in gastric cancer79
Hepatitis C virus core protein-induced loss of LZIP function correlates with cellular transformation45
Endothelin-1 over-expression in astrocytes leads to increased necrotic cell death in the brain after middle cerebral artery occlusion52
Zucker diabetic fatty rats have elevated intestinal microsomal triglyceride transfer protein (MTP), the molecular mechansimsms and implications in obesity and diabetic dylipidemia (oral presentation)56
In vitro gene transfer of BMP-2 and BMP-4 expression vector38
HNF-1 motif is the insulin responsive element in the promoter of microsomal triglyceride transfer protein (MTP) gene43
Astrocytic over-expression of endothelin-1 in mice increases infarct and neurological deficits after experimental stroke38
Generation and characterization of sodium/myo-inositol cotransporter (SMIT) knockout mice49
Role of endothelin-1 in diabetic retinopathy40
Survival effects of endothelin-1 on astrocytes during hypoxic/ischemic injury involve ERK pathway40
Transgenic mice that overexpress endothelin-1 develop hypertension39
Characterization of candidate tumor suppressor gene, DLC-1 in hepatocellular carcinoma60
Functional characterization of human cell cycle related kinase in glioblastoma carcinogenesis35
Role of the NA+-coupled dicarboxylate cotransporter (NADC-1) in obesity and aging42
Aldose reductase gene mutation in db/db mice prevents diabetes-induced blood-retinal barrier breakdown, neuro-retinal apoptosis and glial reactivation in the retina92
Aldose reductase-deficient mice are protected from motor nerve conduction deficit associated with diabetes47
Inhibition of cell growth and induction of apoptosis by human TBX5, a member of the TBX family of developmental regulators59
Aldose reductase local deficiency in the kidney is sufficient to impair urine concertrating mechanism58
Non-invasive monitoring of diabetes-induced cutaneous nerve fiber loss and hypoalgesia in thy1-YFP transgenic mice48
Characterization of the N-myc downstream regulated gene 2 in human glioblastoma50
Down-regulation of mouse aldose reductase mRNA in the Schwann cells but not in the endothelial cells of sciatic nerve by hyperglycemia45
Induction of c-Jun protein expression in the retina of adult golden hamsters following intravitreal injection of sciatic nerve exudate46
Studies on the functions of endothelin-1 using the two-tiered Cre/loxP transgenic system49
Contributions of polyols and oxidative stress in sugar cataracts49
Role of endothelial cell overexpressed endothelin-1 (ET-1) in mouse model of ischemic stroke51
Stimulation of transferrin receptor expression by enhanced heme biosynthesis in murine erythroleukemia cells27
Sodium/myo-inositol co-transporter is important for peripheral nerve development and function44
Expression of hepatocyte growth factor, C-Met, in sex hormone-induced prostate carcinogenesis in Noble rats33
The expression patern of mouse aldose reductase and sorbitol dehydrogenase in the nervous system60
Implications of the AR gene in peripheral nerve integrity and its environmental insults in diabetes38
Oxidative stress and diabetic complications62
Regulation of GAP-43 mRNA in rentinal ganglion cells following axotomy and intravitreal peripheral nerve transplantation60
Aldose reductase in naphthalene cataract40
Over-expression of endothelin-1 in astrocytes exacerbates brain injury induced by transient focal cerebral ischemia58
Characterization of a candidate oncogene, cell cycle related kinase (CCRK), in glioblastoma carcinogenesis47
Novel noninvasive approach to study the pathogenesis of chronic diabetic neuropathy47
Human T-cell leukemia virus type 1 oncoprotein Tax preferentially interacts with a group of cellular coiled-coil proteins45
Role of endothelial cell overexpressed endothelin-1 (ET-1) in mouse model of ischemic stroke50
HTLV-I oncoprotein Tax targets a mitotic checkpoint29
Pathogenesis of Amyotrophic Lateral Sclerosis in neuroblastoma cell-cultural model68
Aldose reductase deficiency in kidney collecting tubules impairs the urine concentrating mechanism71
Study on the role of sodium/myo-iositol co-transporter gene on neuromuscular disorders51
Endothelium-restricted ET-1 over-expression leads to larger infarct accompanied by superoxide production after middle cerebral artery occlusion47
Neuronal and astrocytes differentiation are affected in the endothelin-1 knockout mice37
Novel interaction between xiap-associated factor 1 (XAF1) and nuclear coactivator CBP in colon cancer53
Gene therapy using adeno-associated virus-mediated surviving antisense inhibits angiogenesis and tumour growth in colon cancer60
p53 status determines nuclear factor-kb response in triptolide-induced apoptosis in gastric cancer49
Myo-inositol is important for neuromuscular functions58
Electrophysiological effects and release characteristics in the rat cerebellum74
Serum macrophage migration inhibitory factor as a diagnostic and prognostic biomarker for gastric cancer63
Polyol pathway in diabetic complications42
The transient expression of low affinity neurotrophin receptor (p75) and the co-localization of p75 and Zebrin II in the developing rat cerebellum45
Are promotor variants of the glucokinase gene predictive of the development of diabetes in subjects with impaired glucose tolerance?37
The role of polyol pathway in diabetic cataract36
The hypolipidemic agent, pluronic L-81, down-regulates the gene transcription of MTP through insulin signaling pathway52
AAV mediated VEGF gene therapy to control mandibular condylar growth70
Over-expression of a Dominant Negative Form of OREBP in the Lens Causes Congenital Cataract68
Over-expression of endothelin-1 in astrocytes leads to blood-brain barrier disruption, increased infarct, brain edema and more severe neurological deficits after experimental stroke58
Transgenic mice over-expressing endothelin-1 in endothelial cells have blood-retinal barrier breakdown and lower expression of glial fibrillary acidic protein63
Rapid induction of preproendothelin-1 mRNA in both astrocytes and cerebral endothelial cells of hypoxic-ischemic mouse brain37
Intravitreal peripheral nerve graft enhanced c-Jun expression in sprouting retinal ganglion cells (RGCs) in adult hamsters41
School of Brain Function30
Target disruption of MVDP, an aldose reductase-like gene, results in embryonic lethality42
Real-time quantitative PCR study of genes involved in the generation of endothelium-depedent contractions in the aorta of the spontaneously hypertensive rat55
Delivery of bone morphogenetic proteins 2 anad 4 by use of adeno-associated viral gene therapy48
The regulation of factors that might contribute to peripheral nerve function and nerve blood flow in diabetic mice40
JNK1 Up-Regulates the Expression of XIAP-Associated Factor 1 (XAF1) by a P53-Dependent Pathway in Gastrointestinal Cancer56
Adeno-associated virus mediated long term expression of human TERTC27 polypeptide inhibited glioblastoma carcinogenesis by multiple mechanisms75
Identification and characterization of multiple osmotic response sequences in the human aldose reductase gene49
Characterization of a mutation that causes sorbitol dehydrogenase deficiency in mouse44
Cloning and functional characterization of ornithine-aminotransferase (OAT) gene during xenopus embryonic development47
Structural study of the SAM domain of the deleted in liver cancer 2 (DLC2)59
Osmotic Response Element Binding Protein is essential for water reabsorption in kidney43
Livin, a Novel Member of Inhibitor of Apoptosis, Is Marker of Poor Prognosis in Gastric Cancer51
Alcohol-induced brain injury: A Xenopus laevis model of fetal alcohol syndrome69
Greater infarct size and more severe neurological deficit in transgenic mice overexpressing endothelin-1 in astrocytes after transient focal cerebral ischemia50
Survival effects of endothelin-1 on astrocytes during hypoxic/ischemic injury involve ERK pathway33
Over-expression of peroxiredoxin V treatment protected against alcohol-induced ocular anomalies in developing Xenopus laevis51
Aldose reductase in diabetic complications : from mouse to human49
Possible role of endothelin-1 during hypoxic/ischemic brain injury47
Novel non-invasive approach to study the pathogenesis of chronic diabetic neuropathy in mice57
The polyol pathway and diabetic atherosclerosis73
Inhibitory Effect of Embelin On Colon Carcinogenesis Is Peroxisome Proliferator-Activated Receptor γ (PPARγ)-Dependent97
Over-expression of aldose reductase and an aldose reductase-like gene in human liver cancers may contribute to their resistance to chemotherapy37
Novel gene therapy by rAAV-mediated transfer of human TERTC27 polypeptide in human and rat hepatocellular carcinomas69
Z-2 microsatellite allele of aldose reductase gene is associated with diabetic nephropathy in southern Chinese non-insulin-dependent diabetes mellitus78
Antioxidant enzymes protect Xenopus laevis embryos against alcohol-induced neural injury63
Hypermethylation status around exon 1 of XIAP-associated factor 1 (XAF1) in human gastric andcolon cancer cell lines64
Chromosome 16p12 is associated with variation in blood pressure in southern Chinese40
Up-regulation of vasoconstrictor, endothelin-1 may contribute to peripheral nerve dyfunction and reduced blood flow in hyperglycemic mice53
Regulation of preproendothelin-1gene expression during embryonic development in transgenic mice43
The human interferon-induced transmembrane protein family in colorectal cancer carcinogenesis27
Novel HCC gene therapy by rAAV-mediated transfer of human TERTC27 polypeptide in human and rat hepatocellular carcinoma57
A segment of optic nerve transplanted intravitreally retards death and enhances axonal regneration of retinal ganglion cells in adult hamsters57
Osmotic Response Element Binding Protein is essential for water reabsorption in kidney47
Aldose reductase protects renal collecting tubule epithelial cells from hyperosmolality-induced DNA damage63
Intravitreal optic nerve graft retards death and enhances axonal regeneration of retinal ganglion cells in adult hamsters55
rAAV-mediated long-term expression of endostatin significantly inhibits the progression of HCC83
Upregulation of chondroitin 6-sulfotransferase (C6ST) in rat sciatic nerves after crush-injury44
Chemoprevention of gastric cancer through modulation of Protein Kinase C by non-steroidal anti-inflammatory drugs47
Helicobacter Pylori stimultes release of macrophage migration inhibitory factor in monocytes through its pathogenicity island, but not related to CagA and CagE46
The effect of an intravitreal optic nerve graft on the sprouting and survival of retinal ganglion cells following axotomy60
Aldose reductase-deficient mice are protected from reduction of nerve conduction associated with diabetes54
Transgenic mouse models to study the molecular basis of diabetic neuropahty56
Aldose reductive-deficiency mice show alternated activation of JNK1 in the sciatic nerve under diabetic condition40
Influence of peripheral nerve grafts on the expression of GAP-43 in regenerating retinal ganglion cells in adult hamsters45
Astrocytic endothelin-1 leads to blood-brain barrier disruption resulting in increased infarct, brain edema and more severe neurological deficits after experimental stroke42
Induction of aldose reductase and aldose reductase-like genes in the kidney of diabetic mice44
Molecular approach to understand the regulation and function of endothelin-132
The role of poly(ADP-ribose) polymerase in type 2 diabetes43
Peroxiredoxins in cell signaling and HIV-1 infection96
Efficient infection and treatment of solid tumors by a polypeptide of human telomerase reverse transcriptase (hTERTC27) using an AAV and adenovirus cocktail vector system65
The expression of GAP-43 mRNA in the retinal ganglion cells following peripheral nerve transplantation43


TotJulAugSepOctNovDecJanFebMarAprMayJun
2013/20145075455102355144331333341241
2014/20151473338315120127699252779351229
2015/2016370620242612472113612511495847199726
2016/2017308642019221021671776128100161114563189
2017/20182593238951585088950669105319188159159
2018/201911013941161283533593000000
Ever12466