Dr Chen, Jeng-Haur 陳正豪
Positions and Education
2011 Sep – Assistant Professor, Physiology, University of Hong Kong, Hong Kong.
2006 – 2011 Postdoctoral fellow, Howard Hugh Medical Institute, Department of Medicine, University of Iowa, IA, USA.
2001 – 2005 Ph.D., Physiology, University of Bristol, Bristol, UK.
1994 – 1997 M.Sc., Physiology, National Taiwan University, Taipei, Taiwan.
1990 – 1994 B.Sc., Agricultural Chemistry, National Taiwan University, Taipei, Taiwan.
My research focuses on two main fields. The first is the structure and function of a Cl– channel, the cystic fibrosis transmembrane conductance regulator (CFTR). The overall goal of study is to understand how genetic mutations on CFTR cause a life-threatening disease cystic fibrosis. The second field is the respiratory infectious diseases. We want to know how pathogens affect normal airway epithelial function and what the role of ion transport contributes to the pathogenesis.
For electrophysiology study, we will use the excised inside-out patch-clamp method to study single-channel properties of CFTR and Ussing Chamber method to study transepithelial currents across airway epithelial cells. Several molecular and biochemical methods will be widely utilized in our study.
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