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Professor Poon, Ronnie Tung Ping 潘冬平

Title:
Honorary Clinical Professor

Department:

Contact Information
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Tel:
2255 5907
Office:
QMH 459 

Professor Poon, Ronnie Tung Ping 潘冬平

Title:
Honorary Clinical Professor

Department:

Also Cited As:
Poon, Tung-ping, Ronnie
Poon, R
Poon, RT
Poon, Ronnie T.

Professional Qualifications
YearAwarding InstitutionQualification
MBBS
1999The University of Hong KongMS
2006The University of Hong KongPhD
The Royal College of Surgeons of EdinburghFRCS (Edin)
The Royal College of Surgeons of EdinburghFRCSEd (General Surgery)
Hong Kong Academy of MedicineFHKCS
The Hong Kong Academy of MedicineFHKAM (General Surgery)
Biography

Ten Representative Publications

1. Yong KJ, Gao C, Lim JS, Yan B, Yang H, Dimitrov T, Kawasaki A, Ong CW, Wong KF,    Lee S, Ravikumar S, Srivastava S, Tian X, Poon RT, Fan ST, Luk JM, Dan YY, Salto-Tellez M, Chai L, Tenen DG. Oncofetal gene SALL4 in aggressive hepatocellular carcinoma. The New England Journal of Medicine. 2013 Jun 13;368(24):2266-76.

2. Sung WK, Zheng H, Li S, Chen R, Liu X, Li Y, Lee NP, Lee WH, Ariyaratne PN, Tennakoon C, Mulawadi FH, Wong KF, Liu AM, Poon RT et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nature Genetics. 2012; 44(7):765-9

3.  Lee TK, Murphy SR, Cawley NX, Dhanvantari S, Hewitt ST, Lou H, Lau T, Ma S, Huynh Thanh, Wesley RA, Ng IO, Pacak, Poon RT and Peng Loh. An N-terminal truncated carboxypeptidase E splice isoform induces tumor growth and is a biomarker for predicting future metastasis in human cancers (Corresponding author). Journal of Clinical Investigation 2011. 121:3:880-892 (Impact factor 15.387)

4. Thomas M, Jaffe D, Choti M, Belghiti J, Curley S, Fong Y, Gores G, Kerlan R, Merle P, O'Neil B, Poon RT, Schwartz L, Tepper J, Yao F, Haller D, Mooney M, Venook A. Hepatocellular Carcinoma: Consensus Recommendations of the National Cancer Institute Clinical Trials Planning Meeting.  Journal of Clinical Oncology 2010;28(25):3994-4005 (Impact factor 17.793)

5. Pang R, Law WL, Chu ACY, Poon JT, Lam SC, Chow AKM, Ng L, Cheung LW, Lan XR,   Lan HY, Tan VPY, Yau TC, Poon RT, Wong BCY.  A Subpopulation of CD26+ Cancer Stem Cells with Metastatic Capacity in Human Colorectal Cancer.Cell Stem Cell 2010; 6(6):603-15. (Impact factor 23.563)

6. Wang XQ, Ongkeko WM, Chen L, Yang ZF, Lu P, Chen KK, Lopez JP, Poon RT, and Fan ST. Octamer 4 (Oct4) mediates chemotherapeutic drug resistance in liver cancer cells through a potential a Oct4-AKT-ATP-binding cassette G2 pathway. (Corresponding author). Hepatology 2010; 52(2):528-39. (Impact factor 10.84)

7. Yang ZF, Ho DW, Ng MN, Lau CK, Yu WC, Ngai P, Chu PWK, Lam CT, Poon RT, Fan ST. Significance of CD90+ Cancer Stem Cells in Human Liver Cancer. Cancer Cell 2008;13(2):153-166. (Impact factor 25.288)

8. Ho JWY, Pang RWC, Sun CKW, Yu WC, Fan ST,  Poon RTP. Significance of Circulating Endothelial Progenitor Cells in Hepatocellular Carcinoma. (Corresponding author). Hepatology 2006;44:836-843. (Impact factor 10.84)

9. Poon RTP, Ng IOL, Lau C, Yu WC, Yang ZF, Fan ST, Wong J. Tumor Microvessel Density as a Predictor of Recurrence after Resection Hepatocellular Carcinoma: a Prospective Study. (Corresponding author). Journal of Clinical Oncology 2002;20:1775-1785. (Impact factor 17.793)

10. Poon RTP, Fan ST, Lo CM, Liu CL, Ng IOL, Wong J. Long-term Prognosis after Resection of  Hepatocellular Carcinoma Complicating Hepatitis B-Related Cirrhosis. (Corresponding author) (awarded “classic paper in gastrointestinal cancer research of the year” by the journal). Journal of Clinical Oncology 2000;18:1094-101. (Impact factor 17.793) 

 

Biography

Prof. Ronnie T.P. Poon graduated from the medical school of the University of Hong Kong in 1989 with the award of John Anderson Gold Medal. He also obtained MS & PhD degrees from the University of Hong Kong. He received general surgery residency training at St. Vincent’s Hospital of Sydney, Australia and Queen Mary Hospital, Hong Kong. After completion of residency training, he specialized in hepatobiliary and pancreatic surgery and joined the Department of Surgery of the University of Hong Kong in 1998 as an Assistant Professor. He was promoted to Associate Professor in 1991, Professor of Surgery in 1996 and Chair Professor in 2011. He is the bearer of Suen Chi-Sun Endowed Professorship. He is currently the Chief of the Division of Hepatobiliary and Pancreatic Surgery at Queen Mary Hospital. He has served as Assistant Dean of the Faculty of Medicine from 2001 to 2008.

Prof. Poon’s main clinical and research interest is in hepatobiliary and pancreatic cancers. In particular, he has devoted much of his research effort to improve the outcomes of liver cancer, ranging from surgical resection or ablation for early cancer to molecular targeted therapy for advanced disease. He also has interest in basic research on molecular biology and development of novel therapies for liver cancer. He has published more than 360 original articles in international journals, including papers in top journals such as New England Journal of Medicine, Nature Genetics, Cancer Cell, Cell Stem Cell, Journal of Clinical Oncology, Gastroenterology and Annals of Surgery.  His articles are highly cited and for the past consecutive 5 years, he has been among the top 1% scholar according to the ISI Essential Science Indicators. He has also published 15 invited editorials, 17 book chapters and edited two surgical textbooks. He has delivered over 270 invited lectures in international conferences on his research work, including keynote lectures in international conferences such as World Conference on Interventional Oncology and Annual Congress of American Hepato-pancreato-biliary Association. He has contributed to the establishment of consensus guidelines on management of liver cancer by various international organizations, including Asian-Pacific Association for Study of the Liver and National Cancer Institute of the USA. He is the Chairman of the Scientific Committee of the International Hepato-Pancreato-Biliary Association, the Founding Board and Governing Council Member of the International Liver Cancer Association and Executive Secretary of Asia-Pacific Primary Liver Cancer Expert Association. He also serves as the Chairman of Medical Advisory Board for Asian Foundation for Cancer Research.

Prof. Poon has received several awards for his research accomplishment, including the G.B. Ong Traveling Fellowship in 2001, Outstanding Young Researcher Award of the University of Hong Kong in 2003, the International Guest Scholarship of the American College of Surgeons in 2006, Outstanding Researcher Award of the University of Hong Kong 2007 and James IV Traveling Fellowship for 2007. He has served as Chief Editor of Hepatic Oncology, Associate Editor of the World Journal of Surgery, and he also serves in the editorial board of several surgical, gastroenterology and oncology journals including Cancer Therapy, World Journal of Gastroenterology, HBP Surgery, Journal of Gastrointestinal Surgery and Annals of Surgical Oncology. 

 
Honours, Awards & Prizes
AwardeesAward DateHonours / Awards / PrizesCategory
Ng, KKC
2008-12-01Best Oral Presentation Award - "Survival analysis of re-resection and radiofrequency ablation in the treatment of small recurrent hepatocellular carcinoma": The 6th International Meeting, Hepatocellular Carcinoma: Eastern and Western Experiences, Current Issues of Hepatocellular Carcinoma, Seoul, Korea, 7 - 9 December 2008
Research Achievement
2007-05-01Visiting Professor: Department of Surgery, Mayo Clinic Medical School, Rochester, USA
Research Achievement
2011-01-01The University of Hong Kong Endowed Professorship: Suen Chi-Sun Professorship in Surgery 2011: The University of Hong Kong
Research Achievement
Chan, P
Tai, KS
Cheung, TT
Kowk, PC
Jin, K
Lee, KF
Lap, PB
2011-08-01A multi-center phase II trial of Bevacizumab (B) pre- and post-transarterial chemoembolization (TACE) treatment for patients with localized rnresectable HCC: interim safety analyses: Best Abstract Award, Round Asia Oncology Forum, Chinese Society of Clinical Oncology, Shanghai, China
Research Achievement
2007-01-01James IV Travelling Fellowship 2007: James IV Association of Surgeons
Research Achievement
2007-12-01Outstanding Poster Presentation Award - "Functional characterization of homeoprotein Six1 in hepatocellular carcinoma": The 12th Research Postgraduate Symposium, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 12 - 14 December 2007
Research Achievement
Tam, KH
Yang, Z
2006-11-01Young Investigator Award - "Inhibition of mTOR by RAD001 enhances chemo-sensitivity of hepatocellular carcinoma (HCC)": The 13th Hong Kong International Cancer Congress, Hong Kong, 15 - 17 August 2006
Research Achievement
Geng, W
Cheng, Q
Liu, Y
Liu, X
2010-06-16The potential role of early-phase liver graft injury in induction of late-phase chemoresistance after liver transplantation (Young Investigator Award): The 16th Annual International Congress of the International Liver Transplantation Society, Hong Kong, 16 - 19 June 2010
Research Achievement
Ling, C
Liu, X
Li, C
Leung, ACF
2010-06-16Acute phase liver graft injury significantly mobilized circulating endothelial progenitor cells, myeloid-derived suppressor cells and regulatory T cells (Young Investigator Award): The 16th Annual International Congress of the International Liver Transplantation Society, Hong Kong, 16 - 19 June 2010
Research Achievement
2002-11-01Visiting Professor: Fujian Medical University, China
Research Achievement
Dai, WC
2014-03-01Best Oral Award ("Does spontaneous tumor rupture always have an adverse prognostic impact on patients with resectable hepatocellular carcinoma?"): The 11th World Congress of IHPBA
Research Achievement
2007-01-01International Health Professional of the Year 2007: Research and Advisory Board, International Biographical Centre, Cambridge, England
Research Achievement
2007-01-01Visiting Professor: Department of Surgical Oncology, MD Anderson Cancer Center
Research Achievement
2006-10-01Visiting Professor: University of Indiana, USA
Research Achievement
2005-05-01Honorary member: National Chapter of European Hepatobiliary-Pancreatic Association of Serbia
Research Achievement
2001-06-01GB Ong Travelling Fellowship 2001: GB Ong Fund Trustee
Research Achievement
2005-06-01Visiting Professor: Chiba University, Japan
Research Achievement
2006-09-01Visiting Professor: Thomas Jefferson University
Research Achievement
2008-07-01Advanced Study Institute on Cancer Biomarkers: Croucher Foundation
Research Achievement
2005-03-01Visiting Professor: The Third Military Medical University, china
Research Achievement
2007-12-01Outstanding Researcher Award: The University of Hong Kong
Research Achievement
Lam, CT
Yang, Z
Ngai, PP
2006-09-01Poster Prize: The potential role of brain-derived neurotrophic factor (BDNF) in angiogenesis.: The 2nd European Conference on Tumor Angiogenesis and Antiangiogenic Therapy (ECTA)
Research Achievement
2005-05-01Visiting Professor: The University of Belgrade, Serbia
Research Achievement
Ho, JWY
Sun, KW
2004-02-012004 Young Investigators Award: 2004 Hong Kong-shanghai International Liver Congress
Research Achievement
2003-10-01Outstanding Young Researcher Award 2003: The University of Hong Kong
Research Achievement
Dai, WC
2014-03-01Best Oral Presentation Award (Abstract titled "Outcomes of liver resection for hepatocellular carcinoma with obstructive jaundice"): The 11th World Congress of the International Hepato-Pancreato-Biliary Association, Seoul, Korea, 22-27 March 2014
Research Achievement
Chen, PJ
Curtis, CM
Murphy, PS
Suttle, AB
Gauvin, J
Arumugham, T
Hodge, JP
Dar, MM
2011-11-01Phase I dose-finding study of pazopanib in hepatocellular carcinoma: evaluation of early efficacy, pharmacokinetics, and pharmacodynamics: Best Original Paper Award 2011, Department of Surgery, The University of Hong Kong, Clinical Cancer Research
Research Achievement
2005-10-01International Guest Scholarship 2006: American College of Surgeons
Research Achievement
Dai, WC
2014-03-01Best Oral Presentation Award (Abstract titled "Does spontaneous tumor rupture always have an adverse prognostic impact on patients with resectable hepatocellular carcinoma?"): The 11th World Congress of the International Hepato-Pancreato-Biliary Association, Seoul, Korea, 22-27 March 2014
Research Achievement
Professional Societies
Term PeriodPositionProfessional Societies
03/2005 - nowAssociate DirectorContinuous Medical Education Office, Hong Kong Academy of Medicine
11/2006-nowcommittee memberScientific Committee of International Hepato-pancreato-biliary Association
03/2004 - nowCommittee MemberChinese Chapter of International Hepato-Pancreato-Biliary Association
03/2003 - 10/2005Committee MemberSteering Committee, Asia-Pacific Digestive Week
11/2006-nowCommittee memberResearch Committee of International Hepato-pancreato-biliary Association
12/2004 - nowCommittee MemberPermanent Committee of International Meeting on
6/2006-nowFounding Board MemberInternational Liver Cancer Association
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