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HKU ResearcherPage: Tse, HF
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Professor Tse, Hung Fat
  • Clinical Professor
  • Deputy Director of Institute of Cardiovascular Science and Medicine
  • William M W Mong Professorship in Cardiology
  • Professor, Chair of Cardiovascular Medicine
Project Code Amount Title Funding Year
1 HKU 775613M 952636 Novel Therapeutic Approach for X-linked related Danon Disease  Insight from Patient-specific Pluripotent Stem Cells Platform. 2013/2014
2 HKU 780613M 952636 HERC2 as a regulator of endothelial senescence by modulating SIRT1/LKB1 signaling axis 2013/2014
3 HKU 785013M 649524 Relationship between matrix G1a protein and osteogenic endothelial progenitor cells with vascular and valvular calcification in patients with rheumatoid arthritis: Potential therapeutic role of vitamin K 2013/2014
4 HKU 777713M 736128 Cardiac fibroblasts derived Human induced pluripotent cells for cardiac regeneration 2013/2014
5 01121616 917270 Mutational spectrum for dilated cardiomyopathy in Hong Kong 2013/2014
6 InP/079/13 169643 Platform of Human Pluripotent Stem Cell-derived Mesenchymal Stem Cells for Tissue Regeneration and Industrial Application 2013/2014
7 ITS/150/12 948232 Platform of Human Pluripotent Stem Cell-derived Mesenchymal Stem Cells for Tissue Regeneration and Industrial Application 2012/2013
8 HKU 776912M 950000 Human Induced Pluripotent Stem Cells as a Disease Modeling and Drug Screening Platform for Friedreich Ataxia 2012/2013
9 InP/027/13 220010 Platform of Human Pluripotent Stem Cell-derived Mesenchymal Stem Cells for Tissue Regeneration and Industrial Application 2012/2013
10 HKU 775812M 1164605 Pharmacological induction of leukotriene B4 12-hydroxydehydrogenase (LTB4DH) for the resolution of neutrophil-induced myocardial injury 2012/2013
11 10111531 999000 Mendelian randomization to causally infer the impact of life-long vitamin D deficiency on Cardiovascular disease and death: implications for community-based cardiovascular prevention 2012/2013
12 HKU 763312M 1158894 Does an elevated lipocalin-2 concentration in plasma lead to endothelial dysfunction and hypertension? 2012/2013
13 HKU 778212M 980000 Exploring the role of bone marrow-derived mesenchymal stromal/stem cells in nephropathies 2012/2013
14 HKU 768411M 790000 Effects of chronic periodontitis on endothelial progenitor cells: Molecular mechanisms and clinical implications 2011/2012
15 HKU 785611M 950000 Mechanism and Reversibility of Myocardial Fibrosis in Patients with Diabetic Cardiomyopathy: Role of Aliskiren. 2011/2012
16 HKU 777910M 1200000 Driven Maturation of Embryonic Stem Cell-Derived Cardiomyocytes via Cardiac Hypertrophic Signals 2010/2011
17 HKU8/CRF/10 3600000 Self-Assembled Synthetic Ion Channels: Design, Characterization and Biomedical Applications 2010/2011
18 HKU 782610M 1200000 MRI Investigation of Left Ventricular Structure and Function 2010/2011
20 N_HKU 716/09 744000 Generation of corneal epithelial stem cells from human induced pluripotent stem cells (iPSC) and application for corneal epithelial tissue engineering 2009/2010
21 HKU 777508M 598917 Atrial Mechanical Dyssynchrony and Function in Sinus Node Disease Patients With And Without Atrial Fibrillation: Impacts of Different Modes of Atrial and Ventricular Pacing 2008/2009
22 HKU 777208M 996621 Causes of Dysfunction in Regenerated Endothelium 2008/2009
23 HKU 770108M 1396904 Calcium Signals and Cell Proliferation in Human Cardiac Fibroblasts 2008/2009
24 HKU 774708M 1552564 Long-term Efficacy and Safety of a Gene-based Bio-artificial Pacemaker tested in a large animal Sick Sinus Syndrome Model 2008/2009
25 06070951 771600 A population-based prospective study to investigate the associations of obesity and adipokines with the incidence of cardiovascular disease and cancer 2007/2008
26 HKU 779407M 1104018 Thalassaemia major: a new MRI method for detection and monitoring of heart and liver iron deposition 2007/2008
27 HKU 777707M 700896 Prevalence and clinical implications of exercise-induced left ventricular dyssynchrony detected by echocardiography in patients with coronary artery disease 2007/2008
28 HKU 2/07C 5500000 Vascular dysfunction in obesity and diabetes: from risk prediction to therapeutic intervention 2007/2008
29 HKU 762607M 900039 Do biomarkers of inflammation and obesity predict the development of hypertension in Hong Kong Chinese? 2007/2008
30 HKU 7582/06M 1276550 Endothelial damage and atherosclerosis in obstructive sleep apnea: the role of advanced glycation end products 2006/2007
31 HKU 7555/06M 1335906 A prospective randomized trial of endovascular stent graft repair versus best medical treatment for patients with acute Type B aortic dissection 2006/2007
32 HKU 7490/06M 954500 Genomic and proteomic basis of endothelial dysfunction in regenerated endothelium 2006/2007
33 GHP/027/05 2899045 Development of a Suspension Antibody Array-based Multiplex Immunoassay for Early Diagnosis and Therapeutic Monitoring of Diabetes and Cardiovascular Diseases 2005/2006
34 HKU 7347/03M 624000 Ionic channels of mesenchymal stem cells from bone marrow and cell proliferation 2003/2004
35 ITS/109/02 3859500 Development of multi-feature physiological signal classifier and detector for medical diagnoses 2002/2003
36 HKU 7338/01M 734000 Volume-sensitive chloride current and cell volume regulation in human atrial myocytes 2001/2002
37 HKU 7325/00M 800400 Role of nitric oxide synthase and cyclooxygenase2 in angiogenesis after acute myocardial infarction - therapeutic implication by L-arginine 2000/2001
38 HKU 7307/00M 696000 Study of the mechanisms of vascular homeostasis in obstructive sleep apnoea 2000/2001
39 HKU 469/96M 692000 Electromechanical remodelling of chronically fibrillating atrium after transvenous atrial defibrillation 1996/1997
Principal Investigator
Project Code Amount Title Funding Year
1 17121014 865890 Lower Thoracic Spinal Cord Stimulation for Treatment of Heart Failure with Preserved Ejection Fraction: Insight from a Porcine Model of Hypertensive Cardiomyopathy 2014/2015
2 HKU 780013M 1039239 Effects of Catheter-based Splanchnic Denervation on Blood Pressure Control and Left Ventricular Remodeling in Porcine Model of Hypertensive Cardiomyopathy 2013/2014
3 ITS/303/12 993031 Viral-Vector Integration-Free Human Induced Pluripotent Stem Cells Platform Derived from Urine Samples for Disease Diagnosis and Drug Screening 2012/2013
4 N_HKU 730/12 1027619 Targeted gene correction and disease modeling using Wilson's disease induced pluripotent stem cells 2012/2013
5 HKU 779512M 1348250 Therapeutic Effects and Mechanism of Sympathorenal Axis Modulation by Catheter-based Renal Denervation in Porcine Model of Ischemic Heart Failure 2012/2013
6 T12-705/11 34944000 Personalized Medicine for Cardiovascular Diseases: From Genomic Testing and Biomarkers to Human Pluripotent Stem Cell Platform 2011/2012
7 HKU 781111M 1010000 Attenuation of Left Ventricular Remodeling and Improvement of Myocardial Function with Spinal Cord Stimulation in Post-myocardial Infarction Heart Failure 2011/2012
8 HKU 780110M 1600000 Autologous Induced Pluripotent Stem Cells Derived Cardiomyocytes for Cardiac Repair in Porcine Ischemic Cardiomyopathy 2010/2011
9 HKU 8/CRF/09 6700000 Pluripotent Human Stem Cell Platform for Tissue Regeneration and Drug Screening for Cardiovascular Diseases 2009/2010
10 208207 1965000 Direct endomyocardial injection of autologous bone marrow cells for treatment of patients with "end-stage" ischaemic heart failure 2008/2009
11 HKU 776908M 1129516 Transplantation of Bioengineered Human Embryonic Stem Cell-derived Cardiomyocytes with Mature Electrical Phenotype in Post-infarction Heart Failure Improves Cardiac Function Without Proarrhythmia 2008/2009
12 HKU 7633/06M 1154500 Genetic enrichment of cardiac derivatives from human embryonic stem cells and their bioengineering for cell-based heart therapies 2006/2007
13 N_HKU 722/05 796000 Hypoxia-mediated differentiation of murine and human embryonic stem cells into cardiomyocytes: mechanistic roles of calcium and ion channels 2005/2006
14 HKU 7594/05M 698957 Embryonic stem cell transplantation as a novel therapy for post-infarct left ventricular remodeling 2005/2006
15 HKU 7459/04M 1051280 Functional role of pacemaker current, I(f) in sinoatrial node probed by somatic gene transfer of bioengineered HCN channels in swine 2004/2005
16 203217 1400000 Direct intramyocardial implantation of autologous bone marrow cells for enhancement of neovascularization in patients with "End-Staged" coronary artery disease 2003/2004
17 HKU 7357/02M 816000 Neovascularization of ischemic myocardium by autologous bone marrow cells transplantation 2002/2003



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