Name Card

Professor Guan, Yi 管軼

Title:

Professor, Chair of Emerging Viral Diseases

Professor

Department:

School of Public Health

Faculty:

Li Ka Shing Faculty of Medicine

Principal Investigator

Project Code	Project Title	Amount	Funding Year
HKU 7225/02M	Genetic determinants of influenza virus for inter-species transmission: studies using a reverse genetic approach	1747000	2002
HKU 7334/01M	Molecular evolution studies on H5N1/97 and related avian influenza viruses	1004000	2001
HKU 7512/06M	The role of migratory birds in the transmission of H5N1 Influenza virus in eastern Asia	1630500	2006
HKU 765809M	Long-term surveillance for bat-borne viruses: An insight into viral ecology, evolutionary dynamics, and the source of zoonoses	1900000	2009
06060722	Genomic characterization, population ecology and genetics of H9N2 influenza viruses in southern China	606428	2006
01031022	Genetic characterization of H5N1 influenza viruses isolated from different regions of Southern China	970100	2003
12111252	Infectivity and Transmissibility Study of Avian H9N2 Influenza Viruses in Pigs	990000	2012

Co-Investigator

Project Code	Project Title	Amount	Funding Year
HKU 785612M	Evolution and Risk assessment studies for 2009 pandemic-like reassortant swine influenza viruses from China	1348250	2012
AoE/M-12/06	Control of Pandemic and Inter-pandemic Influenza	76000000	2007
HKU 7542/03M	Genetic variation of the SARS coronavirus: molecular epidemiology and antigenic variation	1012000	2003
06060582	Antiviral drug resistance in H5N1 virus	790000	2006
T11-705/14-N	Viral, Host and Environmental Determinants of Influenza Virus Transmission and Pathogenesis	58000000	2014
N/A	The Zoonotic potential of influenze viruses in Southeastern China	7720751	2001
COVID190223	Studying SARS-CoV-2 related coronavirus in pangolins	680000	2020
HKU 1/05C	Pathogenesis, cell signaling and virus evolution of avian influenza A (H5N1)	4600000	2005
18170432	Exploring the arbovirus diversity among the Aedes and Culex mosquitoes in Hong Kong	1439146	2018
T11-712/19-N	Control of Influenza: Individual and Population Immunity	38611000	2019
C7144-20G	Role of pangolins in the emergence of SARS-CoV-2 and other viruses in humans	5886306	2020
HKU 7335/02M	The application of DNA arrays to characterise the avian influenza gene pool in southern China	876000	2002
N/A	Influenza pandemic preparedness in Asia (Research collaboration with national Institute of Allergy and Infectious Diseases (NIAID), St. Jude Children's Research Hospital, Inc. (SJCRH) and The University of Hong Kong)	1361060	1999
21200342	Characterising the virome of urban rodents in Hong Kong	760778	2021
17127714	Molecular basis for the infectivity and transmissibility of the human isolated A(H7N9) influenza virus in a ferret model	825705	2014
HKU 761907M	Mapping antigenic sites on haemagglutinin antigen (HA) of H5N1 virus with a panel of H5 specific monoclonal antibodies.	385586	2007
03040782	Identification of the possible animal reservoirs for SARS-like coronavirus in southern China	632072	2005
HKU 7356/03M	Roles of segment-specific vRNA sequences of influenza A virus in viral replication, transcription and gene expression	1112000	2003
HKU 7488/05M	Molecular basis of genesis and determinants for pathogenicity of avian influenza H5N1 virus genotype Z	934957	2005
17108417	Genetic characterization and identification of the molecular basis for the increasing infectivity and transmissibility of highly pathogenic H5 influenza virus in mammals	1286938	2017
01030172	The role of influenza virus gene constellation and viral morphology on cytokine induction, pathogenesis and viral virulence	824164	2003
HKU 7459/03M	Viral determinants underlying the increased secretion of pro-inflammatory cytokines in H5N1 infected human macrophages: a mechanism for the unusual severity of human H5N1 disease?	1715400	2003
17150816	Phylogeny-guided assembly of short reads from deep sequencing of microbial samples	590905	2016
01030292	Studies of SARS virus vaccines	805000	2004
17118515	Continuous evolution of H10N8 influenza viruses in chickens and molecular determinants for their infectivity in mammals	1145430	2015
14131402	Molecular determinants for the interspecies transmission of an avian H6N1 virus that caused the human infection in Taiwan	1000000	2014
HKU 7551/03M	A study of antiviral peptides targeting spike and matrix proteins of SARS coronavirus	652000	2003
N/A	Influenza pandemic preparedness in Asia (Research collaboration with national Institute of Allergy and Infectious Diseases (NIAID), St. Jude Children's Research Hospital, Inc. (SJCRH) and The University of Hong Kong)	4519673	2001
HKU 7500/06M	H5N1 virus heterogeneity and mechanisms for adaptation to new hosts	1210692	2006
03040872	Sialic acid and receptor expression in normal respiratory tract, H5N1 influenza and non-avian influenza cases	249564	2004
N/A	Influenza pandemic preparedness in Asia (Research collaboration with national Institute of Allergy and Infectious Diseases (NIAID), St. Jude Children's Research Hospital, Inc. (SJCRH) and The University of Hong Kong)	3523360	2000