HKU ResearcherPage: Nicholls, John Malcolm

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Professor Nicholls, John Malcolm

黎國思

Clinical Professor

Dept:

Dept of Pathology

Faculty:

Li Ka Shing Faculty of Medicine

Co-Investigator

		Project Code	Amount	Title	Funding Year
1		HKU 761208M	415682	Tissue tropism and innate immune responses of respiratory viruses in primary differentiated human respiratory epithelial cells in vitro and in ex-vivo cultures of lung and nasopharynx	2008/2009
2		HKU 7478/03M	1041000	Downregulation of MAD2 expression and its significance in chemodrug sensitization in nasopharyngeal carcinoma cells	2003/2004
3		HKU 7357/02M	816000	Neovascularization of ischemic myocardium by autologous bone marrow cells transplantation	2002/2003
4		HKU 7325/97M	686880	Telomerase activation in nasopharyngeal carcinomas	1997/1998
5		HKU 776110M	606982	The role of Toll-like receptor 10 (TLR10) as an innate immune sensor for respiratory viral infections	2010/2011
6		11101002	875948	Neutrophil mediated host-responses during influenza A virus infection, an in vitro study	2011/2012
7		10091132	936436	The biological and genetic determinants of seasonal influenza A virus replication in the lower respiratory tract	2010/2011
8			180000	Nasopharyngeal Carcinoma (NPC)	2006/2007
9		10091162	909862	Experimental models to study the impact of cigarette smoking on the tropism of the highly pathogenic avian influenza H5N1 virus in human respiratory tract	2010/2011
10		HKU 761210M	1500000	Effect of allogeneic human mesenchymal stem cells on alveolar fluid clearance and protein permeability in human alveolar epithelial cells injured by influenza H5N1 virus infection	2010/2011
11		HKU 773707M	1397226	Effector roles of cytokine cascades in the pathogenesis of human H5N1 disease	2007/2008
12		01030172	824164	The role of influenza virus gene constellation and viral morphology on cytokine induction, pathogenesis and viral virulence	2003/2004
13		HKU 1/05C	4600000	Pathogenesis, cell signaling and virus evolution of avian influenza A (H5N1)	2005/2006

Principal Investigator

		Project Code	Amount	Title	Funding Year
1		03040872	249564	Sialic acid and receptor expression in normal respiratory tract, H5N1 influenza and non-avian influenza cases	2004/2005
2		HKU 774109M	1200000	Influenza and sialic acid linked glycan interactions using virus like pseudoparticles (VLP) and STD-NMR	2009/2010
3		JRS02/97	20000	Analysis of the humoral immune response to the Epstein-Barr virus (EBV)-encoded dUTPase and immunohistochemical detection of the enzyme in nasopharyngeal carcinoma (NPC)	1996/1997
4			15000	Expression of collagen during early fetal development	1989/1990
5		08070842	745568	Susceptibility of the upper respiratory tract to influenza virus infection following desialyation	2007/2008
6		F_HKA03/99	28000	A comparison of molecular changes in nasopharyngeal carciomas from Hong Kong and Northern Africa	1999/2000
7		10090202	556392	Prevention and treatment of swine origin influenza virus (S-OIV) though the use of interferon - an in vivo and ex vivo study	2009/2010
8		HKU 7311/97M	535680	The relationship between cell cycle regulators and Epstein-Barr virus in nasopharyngeal carcinoma	1997/1998
9		04050132	158028	Occult respiratory viral infections in coronial autopsies - a pilot project	2005/2006
10			780475	Investigations into influenza receptor binding and novel therapies in an ex-vivo setting	2009/2010
11			28000	A comparison of molecular changes in nasopharyngeal carciomas from Hong Kong and Northern Africa	2000/2001
12		HKU 773507M	667673	Tissue tropism and cytokine production within the upper and lower respiratory tract of humans following influenza virus infection	2007/2008
13			10000	Analysis of the humoral immune response to the Epstein-Barr virus (EBV)-encoded dUTPase and immunohistochemical detection of the enzyme in nasopharyngeal carcinoma (NPC)	1998/1999
14		G_HK 007/01	28000	Detection of the deleted form of Epstein-Barr Virus (EBV) latent membrane portein 1 (LMP1) in formalin fixed biopsy samples	2001/2002

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