The effect of melatonin in the treatment of thrombocytopenia


Grant Data
Project Title
The effect of melatonin in the treatment of thrombocytopenia
Principal Investigator
Dr Yang, Mo   (Principal investigator)
Duration
12
Start Date
2008-01-01
Completion Date
2008-12-31
Amount
25000
Conference Title
Presentation Title
Keywords
Thrombocytopenia, Melatonin, thrombopoiesis, megakaryocytes, haematopoietic stem cells
Discipline
Blood/Hematology,Paediatrics
Sponsor
Other projects
Grant Type
Queen Mary Hospital Charitable Trust - Training and Research Assistance Scheme
Funding Year
2007/2008
Status
On-going
Objectives
To investigate the mitogenic effect of MLT on in-vitro megakaryocytopoiesis and proplatelet formation; to analyze the effect of MLT on thrombopoiesis in a thrombocytopenic model; to analyze the role of G-protein receptors on megakaryocytopoiesis and proplatelet formation in a G i2-deficient mice.