Effects of GC content and mutational pressure on exon length
Dr Xia, Xuhua (Principal investigator)
RGC General Research Fund (GRF)
HKU Project Code
General Research Fund (GRF)
To evaluate the effect of GC content on exon length by using the huge amount of molecular data already available in molecular databanks; to test the prediction that the effect of GC content on exon length is more pronounced in the mitochondrial genomes than in the nuclear genomes; to assess the frequency of the gene truncation event due to nonsence mutations and the gene elongation event due to stop codons mutating to sense codons; to implement new analytical tools in my program DAMBE, which will be distributed free to reserchers.