The effect of DNA methylation on codon substitution and codon usage bias


Grant Data
Project Title
The effect of DNA methylation on codon substitution and codon usage bias
Principal Investigator
Dr Xia, Xuhua   (Principal investigator)
Duration
24
Start Date
2000-10-01
Completion Date
2002-09-30
Amount
520180
Conference Title
Presentation Title
Sponsor
RGC General Research Fund (GRF)
HKU Project Code
HKU 7265/00M
Grant Type
General Research Fund (GRF)
Funding Year
2000/2001
Status
Completed
Objectives
The project will quantify the effect of DNA methylation on nucleotide, codon and amino acid substitution patters; integrate the methylation effect on codon usage into current hypotheses on codon usage bias; and develop computer programs for comparative sequence anaylsis by automating analytical procedures such as data retrieval from GenBank, data compilation and manipulation, phylogenetic reconstruction, and phylogeny-based comparative analysis.