Immunopathogenesis of tuberculosis in Hong Kong


Grant Data
Project Title
Immunopathogenesis of tuberculosis in Hong Kong
Principal Investigator
Dr Higgins, David Anthony   (Principal investigator)
Co-Investigator(s)
Dr Lowrie   (Co-Investigator)
Mr Bloom   (Co-Investigator)
Dr Skamene   (Co-Investigator)
Dr Chan   (Co-Investigator)
Start Date
1984-12-01
Amount
161460
Conference Title
Presentation Title
Grant Type
World Health Organization (WHO) - General Award
Funding Year
1989/1990
Status
Completed
Objectives
To study immune parameters in tuberculosis patients; to identify humoral and cellular suppressor influences; to compare the immune responsiveness of peripheral blood cells and pleural effusion cells in tuberculosis patients; to ascertain whether any deficiency in production or activity of cytokines is localized to the site of infection; and to establish Epstein-Barr virus-transformed B cell lines from members of multiple case families for analysis with probes for recently-discovered genes conferring resistance or susceptibility to mycobacterial infections.