Hepatitis B virus DNA (HBV-DNA) in Chinese patients with chronic HBV infection and hepatocellular carcinoma (HCC)


Grant Data
Project Title
Hepatitis B virus DNA (HBV-DNA) in Chinese patients with chronic HBV infection and hepatocellular carcinoma (HCC)
Principal Investigator
Dr Lok, Anna Suk Fong   (Principal investigator)
Start Date
1986-07-01
Amount
130000
Conference Title
Presentation Title
HKU Project Code
SRC
Grant Type
Strategic Research Fund (UPGC)
Funding Year
1985/1986
Status
Completed
Objectives
To determine the serum HBV-DNA levels and the molecular state (episomal and/or integrated) HBV-DNA in liver tissue in patients with chronic HBV infection and HCC; to characterize and clone the viral/host integration sites in patients with chronic hepatitis B, cirrhosis and HCC and to determine the mechanism leading to carcinogenesis.