Dietary zinc deficiency and methylation of target tissues DNA in rat


Grant Data
Project Title
Dietary zinc deficiency and methylation of target tissues DNA in rat
Principal Investigator
Dr Fong, Louise Yuk Ying   (Principal investigator)
Start Date
1983-07-01
Amount
15000
Conference Title
Presentation Title
Grant Type
Wing Lung Bank Medical Research Fund
Funding Year
1987/1988
Status
Completed
Objectives
To determine the formation and persistence of the crucial DNA-carcinogen adduct, O6 methylgnanine (O6-MG) in tumour target-tissues (liver, oesophagus, forestomach, kidney) following an intraperitoneal injection of a liver carcinogen: dimethylnitrosamine (DMN) or MBN in zinc deficient and control zinc-sufficient rats.