Prevalence of hepatitis C infection in Chinese pregnant women and its relationship to hepatitis B carrier status and liver function


Grant Data
Project Title
Prevalence of hepatitis C infection in Chinese pregnant women and its relationship to hepatitis B carrier status and liver function
Principal Investigator
Dr Lam, Helena Sze Wing   (Principal investigator)
Co-Investigator(s)
Professor Lao Terence Tzu Hsi   (Co-Investigator)
Dr Ni Guoxin   (Co-Investigator)
Duration
15
Start Date
1996-04-01
Completion Date
1997-06-30
Amount
64570
Conference Title
Presentation Title
Keywords
hepatitis
Discipline
Others - Medicine, Dentistry and Health
Sponsor
Other projects
Grant Type
Health Services Research Fund - Full Grants
Funding Year
1996/1997
Status
Completed
Objectives
To determine the prevalence of hepatitis C seropositivity in pregnant Chinese women who are tested negative for the hepatitis B surface antigen; to determine the prevalence of hepatitis C seropositivity among pregnant Chinese women who are carriers of the heptaitis B surface antigen; to determine the incidence of abnormal liver function test among mothers who are carriers of hepatitis B surface antigen, and its relationship with hepatitis C seropositivity; to determine the incidence of HCV-RNA seropositivity in mothers with positive HCV antibody and its relationship with liver function; to determine the incidence of vertical transmission of hepatitis C from the mothers to their infants; to evaluate the cost-effectiveness of a screening programme of hepatitis C seropositivity among pregnant women who are carriers of hepatitis B surface antigen.