Next-generation high throughput diagnostics-on-a-chip system based on on droplet microfluidics


Grant Data
Project Title
Next-generation high throughput diagnostics-on-a-chip system based on on droplet microfluidics
Principal Investigator
Dr Shum, Ho Cheung   (Project coordinator)
Co-Investigator(s)
Dr Kong Tiantian   (Co-Investigator)
Professor Zhang Hui Sheng   (Co-Investigator)
Duration
24
Start Date
2016-09-01
Completion Date
2018-08-31
Amount
2163789
Conference Title
Presentation Title
Keywords
Next-generation high throughput diagnostics, droplet microfluidics
Discipline
Others - Mechanical, Production and Industrial Engineering
Panel
Engineering
HKU Project Code
GHP/024/16GD
Grant Type
Guangdong-Hong Kong Technology Cooperation Funding Scheme
Funding Year
2016/2017
Status
On-going
Objectives
The proposed project aims to develop the mechanical and fluidic parts of equipment that are needed to miniaturize and automate in vitro diagnostics. While miniaturization using microfluidic devices have been proven to improve the speed, increase the throughput and reduce the costs of diagnostics, integration with existing practices by medical doctors remains a challenge. In this project, we propose direct integration of microfluidic manipulations with microwell plates, which are common used to collect and analyze samples. Successful completion of the project will help unleash the power of microfluidic handling of samples and realize the promises that have long been demonstrated in academic laboratories. Thus, the economic potential and healthcare benefits will be enormous. We will demonstrate a microfluidic-based system that can process and analyze large quantities of clinical samples with increasing efficiency and extraordinary user-friendness. The finished equipment should directly interface the clinical samples collected by doctors with any microfluidic-based bio-chips. The successful integration between existing practices in clinics and next-generation bio-chips will translate to great market value, facilitating the upgrading of the medical device industries within the Pearl Delta Region, including Hong Kong.