Use of Peri-operative Terlipressin in Patients with Pre-operative Type 1 Hepatorenal Syndrome in Adult Liver Transplantation – A Randomized Controlled Trial


Grant Data
Project Title
Use of Peri-operative Terlipressin in Patients with Pre-operative Type 1 Hepatorenal Syndrome in Adult Liver Transplantation – A Randomized Controlled Trial
Principal Investigator
Dr Chok, Kenneth Siu Ho   (Principal investigator)
Co-Investigator(s)
Dr Ma Ka Wing   (Co-Investigator)
Professor Lo Chung Mau   (Co-Investigator)
Dr Cheung Tan To   (Co-Investigator)
Dr Wong Cho Lam Tiffany   (Co-Investigator)
Dr Dai Jeff   (Co-Investigator)
Dr Sin Sui Ling   (Co-Investigator)
Dr She Brian Wong Hoi   (Co-Investigator)
Dr Chan Albert Chi Yan   (Co-Investigator)
Dr Fung James Yan Yue   (Co-Investigator)
Dr Lo Kevin   (Co-Investigator)
Duration
24
Start Date
2016-06-30
Completion Date
2018-06-29
Amount
150000
Conference Title
Presentation Title
Keywords
Outcomes, Liver Transplant, Hepatorenal syndrome, Renal failure, Terlipressin, Liver failure
Discipline
Transplantation,Anaesthesia
Panel
Medicine
Sponsor
Block Grant Earmarked for Research (104)
HKU Project Code
201605159005
Grant Type
Seed Fund for Basic Research
Funding Year
2015/2016
Status
On-going
Objectives
A prospective randomised controlled trial comparing use of peri-operative terlipressin is proposed at our centre. The objectives of the trial are (1) to test the hypothesis that peri-operative terlipressin entails a better postoperative renal function after LT in pre-operative type-1 HRS patients (2) to see whether longer term renal function can be improved in pre-operative HRS patients.