A longitudinal multimodal MRI investigation for clinical and functional outcome prediction in individuals at clinical high-risk for psychosis: a prospective 2-year follow-up study


Grant Data
Project Title
A longitudinal multimodal MRI investigation for clinical and functional outcome prediction in individuals at clinical high-risk for psychosis: a prospective 2-year follow-up study
Principal Investigator
Dr Chang, Wing Chung   (Principal investigator)
Co-Investigator(s)
Dr Chan Kit Wa   (Co-Investigator)
Dr Geng Xiujuan   (Co-Investigator)
Professor Sham Pak Chung   (Co-Investigator)
Dr Lee Ho Ming Edwin   (Co-Investigator)
Dr Hui Christy Lai Ming   (Co-Investigator)
Dr Cheung Charlton   (Co-Investigator)
Professor Chen Eric Yu Hai   (Co-Investigator)
Duration
36
Start Date
2016-01-01
Completion Date
2018-12-31
Amount
1026712
Conference Title
Presentation Title
Keywords
Clinical high risk, At risk mental state, Psychosis prediction, Longitudinal neuroimaging, Multimodal MRI
Discipline
Psychosocial and Behavioural Research
Panel
Biology and Medicine (M)
Sponsor
RGC General Research Fund (GRF)
HKU Project Code
17124715
Grant Type
General Research Fund (GRF)
Funding Year
2015/2016
Status
On-going
Objectives
2 To examine predictive capacity of multimodal MRI measures on functional outcome 3 To elucidate inter-relationships between abnormalities of brain structures and functional connectivity in CHR sample 4 To investigate relationship between MRI parameters and symptom and cognitive variables 5 To examine whether integrating MRI measures with clinical and cognitive variables improves psychosis prediction