The role of SUMO-specific protease SENP1 in liver cancer


Grant Data
Project Title
The role of SUMO-specific protease SENP1 in liver cancer
Principal Investigator
Professor Ng, Irene Oi Lin   (Principal investigator)
Co-Investigator(s)
Dr Cui Chunping   (Co-Investigator)
Dr Wong Carmen Chak Lui   (Co-Investigator)
Duration
36
Start Date
2015-10-01
Completion Date
2018-09-30
Amount
1198878
Conference Title
Presentation Title
Keywords
hepatocellular carcinoma, SENP1, hypoxia, tumor growth, metastasis
Discipline
Cancer
Panel
Biology and Medicine (M)
Sponsor
RGC General Research Fund (GRF)
HKU Project Code
17111315
Grant Type
General Research Fund (GRF)
Funding Year
2015/2016
Status
On-going
Objectives
2 To investigate the role of SENP1 on liver cancer stem cells. 3 To characterize the functional roles of SENP1 in HCC. 4 To delineate the molecular mechanisms of SENP1 and its interaction with HIF in HCC.