Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) in small-for-size liver remnant : a prospective safety and feasibility study.


Grant Data
Project Title
Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) in small-for-size liver remnant : a prospective safety and feasibility study.
Principal Investigator
Dr Chan, Albert Chi Yan   (Principal investigator)
Co-Investigator(s)
Professor Lo Chung Mau   (Co-Investigator)
Professor Poon Ronnie Tung Ping   (Co-Investigator)
Professor Man Kwan   (Co-Investigator)
Duration
36
Start Date
2015-07-01
Completion Date
2018-06-30
Amount
896929
Conference Title
Presentation Title
Keywords
ALPPS, hepatectomy, hepatocellular carcinoma, liver remnant, portal vein ligation
Discipline
Surgical Research
Panel
Biology and Medicine (M)
Sponsor
RGC General Research Fund (GRF)
HKU Project Code
17114915
Grant Type
General Research Fund (GRF)
Funding Year
2015/2016
Status
On-going
Objectives
2 To measure the change in left portal flow before and after ALPPS procedure using intraoperative doppler ultrasonography 3 To measure the change in portal pressure before and after ALPPS procedure 4 To record the complication rate and mortally rate related to the ALPPS procedure 5 To measure the cellular proliferative activity in the left liver by immunohistochemical staining for Ki-67 and VEGF before and after the ALPPS procedure 6 To measure the change in intraoperative indocyanine green clearance rate of the liver remnant before and after ALPPS