Role of PD1-Based Vaccine-Elicited CD8+ T Lymphocytes in Modulating MDSC-associated Immunosuppression


Grant Data
Project Title
Role of PD1-Based Vaccine-Elicited CD8+ T Lymphocytes in Modulating MDSC-associated Immunosuppression
Principal Investigator
Professor Chen, Zhiwei   (Principal investigator)
Co-Investigator(s)
Dr Cheung Ka Loon Allen   (Co-Investigator)
Dr Tan Zhiwu   (Co-Investigator)
Duration
36
Start Date
2016-01-01
Completion Date
2018-12-31
Amount
977457
Conference Title
Presentation Title
Keywords
HIV, AIDS, T cell, Vaccine, Cure
Discipline
Allergy/Immunology
Panel
Biology and Medicine (M)
Sponsor
RGC General Research Fund (GRF)
HKU Project Code
17122915
Grant Type
General Research Fund (GRF)
Funding Year
2015/2016
Status
On-going
Objectives
2 To enhance the efficacy of vaccine-elicited CD8+ T cells in eliminating HIV-1 infected cells by reducing MDSC responses (year 1.5-3) We will focus on critical experiments and minimal number of mice due to the budge cut.