Functional and Mechanistic Investigation of Frequent p53 Gain-of-Function Mutations in Esophageal Squamous Cell Carcinoma


Grant Data
Project Title
Functional and Mechanistic Investigation of Frequent p53 Gain-of-Function Mutations in Esophageal Squamous Cell Carcinoma
Principal Investigator
Professor Lung, Maria Li   (Principal investigator)
Duration
36
Start Date
2015-09-01
Completion Date
2018-08-31
Amount
1168311
Conference Title
Presentation Title
Keywords
p53, esophageal cancer, gain-of-function mutation, orthotopic model, metastasis
Discipline
Cell Biology
Panel
Biology and Medicine (M)
Sponsor
RGC General Research Fund (GRF)
HKU Project Code
17109515
Grant Type
General Research Fund (GRF)
Funding Year
2015/2016
Status
On-going
Objectives
2 Perform mechanistic and signaling studies of gain-of-function p53 mutants in ESCC