Myometrial cells modulate the activities of endometrial mesenchymal-like stem cells


Grant Data
Project Title
Myometrial cells modulate the activities of endometrial mesenchymal-like stem cells
Principal Investigator
Professor Ng, Ernest Hung Yu   (Principal investigator)
Co-Investigator(s)
Dr Chan Rachel Wah Shan   (Co-Investigator)
Professor Yeung William Shu Biu   (Co-Investigator)
Dr Lee Calvin Kai Fai   (Co-Investigator)
Duration
36
Start Date
2016-01-01
Completion Date
2018-12-31
Amount
889107
Conference Title
Presentation Title
Keywords
endometrial stem cells, matrix metalloproteinase 3, myometrial cells, Wnt signaling
Discipline
Reproduction
Panel
Biology and Medicine (M)
Sponsor
RGC General Research Fund (GRF)
HKU Project Code
17125815
Grant Type
General Research Fund (GRF)
Funding Year
2015/2016
Status
On-going
Objectives
2 To determine the role of Wnt signalling in the myometrial cells-induced increase in clonogenicity and proliferation of endometrial mesenchymal-like stem cells. 3 To study the actions of myometrial cell-derived matrix metalloproteinase-3 on clonogenicity and proliferation of the endometrial mesenchymal-like stem cells.