Results 1 to 20 of 29
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Appl1 transgenic mice are protected from high fat diet induced cardiac dysfunctionPark, M; Wu, D; Park, T; Choi, C; Li, R; Cheng, KY; Xu, A; Sweeney, G201337
Traf6-mediated ubiquitination of appl1 enhances hepatic actions of insulin by promoting the membrane translocation of aktCheng, KY; Lam, KSL; Wang, Y; Wu, D; Zhang, M; WANG, B; Li, X; Hoo, RLC; HUANG, Z; Sweeney, G; Xu, A201335
Globular adiponectin induces lkb1/ampk-dependent glucose uptake via actin cytoskeleton remodelingVu, V; Bui, P; Eguchi, M; Xu, A; Sweeney, G201335
Improved functional recovery to I/R injury in hearts from lipocalin-2 deficiency mice: restoration of mitochondrial function and phospholipids remodelingYang, B; Fan, P; Xu, A; Lam, KSL; Berger, T; Mak, TW; Tse, HF; Yue, JWS; Song, E; Vanhoutte, PM; Sweeney, G; Wang, Y2012154
Adiponectin corrects high-fat diet-induced disturbances in muscle metabolomic profile and whole-body glucose homeostasisLiu, Y; Turdi, S; Park, T; Morris, NJ; Deshaies, Y; Xu, A; Sweeney, G201225
APPL1 potentiates insulin secretion in pancreatic β cells by enhancing protein kinase Akt-dependent expression of SNARE proteins in miceCheng, KKY; Lam, KSL; Wu, D; Wang, Y; Sweeney, G; Hoo, RLC; Zhang, J; Xu, A2012199
Emerging clinical and experimental evidence for the role of lipocalin-2 in metabolic syndromeJang, Y; Lee, JH; Wang, Y; Sweeney, G2012276
Lipocalin-2 induces cardiomyocyte apoptosis by increasing intracellular iron accumulationXu, G; Ahn, J; Chang, S; Eguchi, M; Ogier, A; Han, S; Park, Y; Shim, C; Jang, Y; Yang, B; Xu, A; Wang, Y; Sweeney, G2012109
Delivery of adiponectin gene to skeletal muscle using ultrasound targeted microbubbles improves insulin sensitivity and whole body glucose homeostasisVu, V; Liu, Y; Sen, S; Xu, A; Sweeney, G201219
Selective inactivation of c-Jun NH 2-terminal kinase in adipose tissue protects against diet-induced obesity and improves insulin sensitivity in both liver and skeletal muscle in miceZhang, X; Xu, A; Chung, SK; Cresser, JHB; Sweeney, G; Wong, RLC; Lin, A; Lam, KSL2011193
Globular adiponectin, acting via AdipoR1/APPL1, protects H9c2 cells from hypoxia/reoxygenation-induced apoptosisPark, M; Youn, B; Zheng, XL; Wu, D; Xu, A; Sweeney, G2011266
APPL1 counteracts obesity-induced vascular insulin resistance and endothelial dysfunction by modulating the endothelial production of nitric oxide and endothelin-1 in miceWang, Y; Cheng, KKY; Lam, KSL; Wu, D; Wang, Y; Huang, Y; Vanhoutte, PM; Sweeney, G; Li, Y; Xu, A2011155
Carnitine palmitoyltransferase 1A prevents fatty acid-induced adipocyte dysfunction through suppression of c-Jun N-terminal kinaseGao, X; Li, K; Hui, X; Kong, X; Sweeney, G; Wang, Y; Xu, A; Teng, M; Liu, P; Wu, D2011307
Lipocalin-2 deficiency attenuates insulin resistance associated with aging and obesityLaw, IKM; Xu, A; Lam, KSL; Berger, T; Mak, TW; Vanhoutte, PM; Liu, JTC; Sweeney, G; Zhou, M; Yang, B; Wang, Y2010417
An APPL1-AMPK signaling axis mediates beneficial metabolic effects of adiponectin in the heartFang, X; Palanivel, R; Cresser, J; Schram, K; Ganguly, R; Thong, FSL; Tuinei, J; Xu, A; Abel, ED; Sweeney, G2010121
APPL1 antagonises Tribble 3 in regulating hepatic glucose production through fine-tuning insulin-evoked Akt signallingCheng, KKY; Iglesias, MA; Lam, KSL; Sweeney, G; Zhu, W; Kraegen, EW; Xu, A2010103
Leptin prevents the metabolic effects of adiponectin in L6 myotubesFang, X; Fetros, J; Dadson, KE; Xu, A; Sweeney, G200974
APPL1 Potentiates Insulin-Mediated Inhibition of Hepatic Glucose Production and Alleviates Diabetes via Akt Activation in MiceCheng, KKY; Iglesias, MA; Lam, KSL; Wang, Y; Sweeney, G; Zhu, W; Vanhoutte, PM; Kraegen, EW; Xu, A2009501
Enhanced susceptibility of Cpt1c knockout mice to glucose intolerance induced by a high-fat diet involves elevated hepatic gluconeogenesis and decreased skeletal muscle glucose uptakeGao, XF; Chen, W; Kong, XP; Xu, AM; Wang, ZG; Sweeney, G; Wu, D2009172
Functional significance of skeletal muscle adiponectin production, changes in animal models of obesity and diabetes, and regulation by rosiglitazone treatmentLiu, Y; Chewchuk, S; Lavigne, C; Brûlé, S; Pilon, G; Houde, V; Xu, A; Marette, A; Sweeney, G2009270
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