Results 1 to 20 of 47
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TypeTitleAuthor(s)YearViews
Preclinical evaluation of the mTOR-PI3K inhibitor BEZ235 in nasopharyngeal cancer models
Journal:
Cancer Letters
Ma, BBY; Lui, VWY; Hui, CWC; Lau, CPY; Wong, CH; Hui, EP; Ng, MHL; Cheng, SH; Tsao, SW; Tsang, C-M; Cheung, CSF; Ho, K; Chan, ATC201463
 
Activity of the MEK inhibitor selumetinib (AZD6244; ARRY-142886) in nasopharyngeal cancer cell lines
Journal:
Investigational New Drugs
Ma, BBY; Lui, VWY; Cheung, CS; Lau, CPY; Ho, K; Hui, EP; Tsui, SKW; Ng, MH; Cheng, SH; Ng, PKS; Tsao, SW; Chan, ATC201376
 
Preclinical evaluation of combined TKI-258 and RAD001 in hepatocellular carcinoma
Journal:
Cancer Chemotherapy and Pharmacology
Chan, SL; Wong, C-H; Lau, CPY; Zhou, Q; Hui, CWC; Lui, VWY; Ma, BBY; Chan, ATC; Yeo, W201349
 
Preclinical evaluation of the AKT inhibitor MK-2206 in nasopharyngeal carcinoma cell lines
Journal:
Investigational New Drugs
Ma, BBY; Lui, VWY; Hui, CWC; Lau, CPY; Wong, C-H; Hui, EP; Ng, MH; Tsao, SW; Li, Y; Chan, ATC201363
 
K252a induces anoikis-sensitization with suppression of cellular migration in Epstein-Barr Virus (EBV)-associated nasopharyngeal carcinoma cells
Journal:
Investigational New Drugs
Publisher:
Springer New York LLC. The Journal's web site is located at http://springerlink.metapress.com/openurl.asp?genre=journal&issn=0167-6997
Ng, YK; Wong, EYL; Lau, CPY; Chan, JPL; Wong, SCC; Chan, ASK; Kwan, MPC; Tsao, SW; Tsang, CM; Lai, PBS; Chan, ATC; Lui, VWY2012191
 
The human cadherin 11 is a pro-apoptotic tumor suppressor modulating cell stemness through Wnt/β-catenin signaling and silenced in common carcinomas
Journal:
Oncogene
Publisher:
Nature Publishing Group. The Journal's web site is located at http://www.nature.com/onc
Li, L; Ying, J; Li, H; Zhang, Y; Shu, X; Fan, Y; Tan, J; Cao, Y; Tsao, SW; Srivastava, G; Chan, ATC; Tao, Q2012196
 
Hypoxia-targeting by tirapazamine (TPZ) induces preferential growth inhibition of nasopharyngeal carcinoma cells with Chk1/2 activation
Journal:
Investigational New Drugs
Publisher:
Springer New York LLC. The Journal's web site is located at http://springerlink.metapress.com/openurl.asp?genre=journal&issn=0167-6997
Hong, B; Lui, VWY; Hui, EP; Ng, MHL; Cheng, SH; Sung, FL; Tsang, CM; Tsao, SW; Chan, ATC2011342
 
FGF8b oncogene mediates proliferation and invasion of Epstein-Barr virus-associated nasopharyngeal carcinoma cells: Implication for viral-mediated FGF8b upregulation
Journal:
Oncogene
Publisher:
Nature Publishing Group. The Journal's web site is located at http://www.nature.com/onc
Lui, VWY; Yau, DMS; Cheung, CSF; Wong, SCC; Chan, AKC; Zhou, Q; Wong, EYL; Lau, CPY; Lam, EKY; Hui, EP; Hong, B; Hui, CWC; Chan, ASK; Ng, PKS; Ng, YK; Lo, KW; Tsang, CM; Tsui, SKW; Tsao, SW; Chan, ATC2011556
 
Inhibition of c-Met downregulates TIGAR expression and reduces NADPH production leading to cell death
Journal:
Oncogene
Publisher:
Nature Publishing Group. The Journal's web site is located at http://www.nature.com/onc
Lui, VWY; Wong, EYL; Ho, K; Ng, PKS; Lau, CPY; Tsui, SKW; Tsang, CM; Tsao, SW; Cheng, SH; Ng, MHL; Ng, YK; Lam, EKY; Hong, B; Lo, KW; Mok, TSK; Chan, ATC; Mills, GB2011406
 
The epigenetic modifier PRDM5 functions as a tumor suppressor through modulating WNT/β-catenin signaling and is frequently silenced in multiple tumors
Journal:
PLoS One
Publisher:
Public Library of Science. The Journal's web site is located at http://www.plosone.org/home.action
Shu, XS; Geng, H; Li, L; Ying, J; Ma, C; Wang, Y; Poon, FF; Wang, X; Ying, Y; Yeo, W; Srivastava, G; Tsao, SW; Yu, J; Sung, JJY; Huang, S; Chan, ATC; Tao, Q2011265
 
A novel isoform of the 8p22 tumor suppressor gene DLC1 suppresses tumor growth and is frequently silenced in multiple common tumors
Journal:
Oncogene
Publisher:
Nature Publishing Group. The Journal's web site is located at http://www.nature.com/onc
Low, JSW; Tao, Q; Ng, KM; Goh, HK; Shu, XS; Woo, WL; Ambinder, RF; Srivastava, G; Shamay, M; Chan, ATC; Popescu, NC; Hsieh, WS2011156
 
Preclinical evaluation of sunitinib as single agent or in combination with chemotherapy in nasopharyngeal carcinoma
Journal:
Investigational New Drugs
Hui, EP; Lui, VWY; Wong, CSC; Ma, BBY; Lau, CPY; Cheung, CSF; Ho, K; Cheng, S-H; Ng, MHL; Chan, ATC201158
 
Reverse phase protein array identifies novel anti-invasion mechanisms of YC-1
Journal:
Biochemical Pharmacology
Hong, B; Lui, VWY; Hui, EP; Lu, Y; Leung, HSY; Wong, EYL; Cheng, S-H; Ng, MHL; Mills, GB; Chan, ATC201068
 
A small molecule inhibitor of NF-κB, dehydroxymethylepoxyquinomicin (DHMEQ), suppresses growth and invasion of nasopharyngeal carcinoma (NPC) cells
Journal:
Cancer Letters
Publisher:
Elsevier Ireland Ltd. The Journal's web site is located at http://www.elsevier.com/locate/canlet
Wong, JHT; Lui, VWY; Umezawa, K; Ho, Y; Wong, EYL; Ng, MHL; Cheng, SH; Tsang, CM; Tsao, SW; Chan, ATC2010422
 
An RNA-directed nucleoside anti-metabolite, 1-(3-C-ethynyl-beta-d-ribo-pentofuranosyl)cytosine (ECyd), elicits antitumor effect via TP53-induced Glycolysis and Apoptosis Regulator (TIGAR) downregulation
Journal:
Biochemical Pharmacology
Publisher:
Elsevier Inc. The Journal's web site is located at http://www.elsevier.com/locate/biochempharm
Lui, VWY; Lau, CPY; Cheung, CSF; Ho, K; Ng, MHL; Cheng, SH; Hong, B; Tsao, SW; Tsang, CM; Lei, KIK; Yamasaki, Y; Mita, A; Chan, ATC2010394
 
The activity of mTOR inhibitor RAD001 (everolimus) in nasopharyngeal carcinoma and cisplatin-resistant cell lines
Journal:
Investigational New Drugs
Publisher:
Springer New York LLC. The Journal's web site is located at http://springerlink.metapress.com/openurl.asp?genre=journal&issn=0167-6997
Ma, BBY; Lui, VWY; Hui, EP; Lau, CPY; Ho, K; Ng, MHL; Cheng, SH; Tsao, SW; Chan, ATC2010400
 
KRAB zinc finger protein ZNF382 is a proapoptotic tumor suppressor that represses multiple oncogenes and is commonly silenced in multiple carcinomas
Journal:
Cancer Research
Publisher:
American Association for Cancer Research. The Journal's web site is located at http://cancerres.aacrjournals.org/
Cheng, Y; Geng, H; Cheng, SH; Liang, P; Bai, Y; Li, J; Srivastava, G; Ng, MHL; Fukagawa, T; Wu, X; Chan, ATC; Tao, Q2010191
 
The preclinical activity of the histone deacetylase inhibitor PXD101 (belinostat) in hepatocellular carcinoma cell lines
Journal:
Investigational New Drugs
Ma, BBY; Sung, F; Tao, Q; Poon, FF; Lui, VW; Yeo, W; Chan, SL; Chan, ATC201049
 
Erratum: Preclinical activity of gefitinib in non-keratinizing nasopharyngeal carcinoma cell lines and biomarkers of response (Investigational New Drugs DOI: 10.1007/s10637-009-9316-7)
Journal:
Investigational New Drugs
Publisher:
Springer New York LLC. The Journal's web site is located at http://springerlink.metapress.com/openurl.asp?genre=journal&issn=0167-6997
Ma, BBY; Lui, VWY; Poon, FF; Wong, SCC; To, KF; Wong, E; Chen, H; Lo, KW; Tao, Q; Ng, MHL; Cheng, SH; Chan, ATC2010577
 
Preclinical activity of gefitinib in non-keratinizing nasopharyngeal carcinoma cell lines and biomarkers of response
Journal:
Investigational New Drugs
Publisher:
Springer New York LLC. The Journal's web site is located at http://springerlink.metapress.com/openurl.asp?genre=journal&issn=0167-6997
Ma, BBY; Lui, VWY; Poon, FF; Wong, SCC; To, KF; Wong, E; Chen, H; Lo, KW; Tao, Q; Chan, ATC2010601
 
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